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Wei-Wei Gao

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Articles 94
Citations 723
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Recent Articles
1.
Zhang J, Cao M, Hou T, Li B, Gu C, Han Z, et al.
Bioorg Chem . 2025 Mar; 158:108336. PMID: 40058225
In this study, 30 tilmicosin-hydrazone derivatives were designed using MOE software. Six candidate molecules with strong binding affinity to DNA or DNA-Topo II complexes, as indicated by molecular docking results,...
2.
Lee C, Lui P, Gao W, Gao Z
Bioengineering (Basel) . 2025 Jan; 11(12. PMID: 39767998
In experimental pain studies involving animals, subjective pain reports are not feasible. Current methods for detecting pain-related behaviors rely on human observation, which is time-consuming and labor-intensive, particularly for lengthy...
3.
Park K, Gao W, Zheng J, Oh K, Kim I, You S
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39408943
Acute kidney injury (AKI) constitutes a severe condition characterized by a sudden decrease in kidney function. Utilizing lineage-restricted stem/progenitor cells, directly reprogrammed from somatic cells, is a promising therapeutic option...
4.
Huang S, Li B, Pang X, Gao W
BMC Infect Dis . 2024 Sep; 24(1):953. PMID: 39261752
Objective: The aim of this study was to evaluate the effectiveness and safety of the nine most widely studied Vonoprazan (VPZ)-based treatment regimens along with traditional Proton pump inhibitor (PPI)-based...
5.
Ying T, Zhuang L, Xu S, Zhang S, Huang L, Gao W, et al.
Am J Alzheimers Dis Other Demen . 2024 Aug; 39:15333175241275215. PMID: 39133478
Objective: To assess the role of Machine Learning (ML) in identification critical factors of dementia and mild cognitive impairment. Methods: 371 elderly individuals were ultimately included in the ML analysis....
6.
Zang Z, Wang Y, Battini N, Gao W, Zhou C
Eur J Med Chem . 2024 Jun; 275:116626. PMID: 38944934
The global microbial resistance is a serious threat to human health, and multitargeting compounds are considered to be promising to combat microbial resistance. In this work, a series of new...
7.
Zang Z, Gao W, Zhou C
Bioorg Chem . 2024 May; 148:107451. PMID: 38759357
Aminothiazolyl coumarins as potentially new antimicrobial agents were designed and synthesized in an effort to overcome drug resistance. Biological activity assay revealed that some target compounds exhibited significantly inhibitory efficiencies...
8.
Zeng J, Gao W, Yang H, Wang Y, Mei Y, Liu T, et al.
Eur J Pharmacol . 2024 Mar; 972:176523. PMID: 38552937
The spinal cord microglia play a pivotal role in neuroinflammation and neuropathic pain (NP). Sodium tanshinone IIA sulfonate (STS), a derivative of tanshinone IIA, has anti-inflammatory and anti-hyperalgesic effects. However,...
9.
Song S, Zhao X, Yang X, Ding Y, Ren F, Pang X, et al.
ACS Appl Mater Interfaces . 2024 Mar; 16(13):16011-16028. PMID: 38529951
Superbug infections and transmission have become major challenges in the contemporary medical field. The development of novel antibacterial strategies to efficiently treat bacterial infections and conquer the problem of antimicrobial...
10.
Yang X, Ding Y, Song S, Wang W, Huang S, Pang X, et al.
Biomater Sci . 2024 Feb; 12(6):1558-1572. PMID: 38305728
In this work, positively charged -carbazoleacetic acid decorated CuO nanoparticles (CuO-CAA NPs) as novel biocompatible nanozymes have been successfully prepared through a one-step hydrothermal method. CuO-CAA can serve as a...