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Veronique Debacker

Explore the profile of Veronique Debacker including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 160
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Recent Articles
1.
Duthoo E, Beyls E, Backers L, Gudjonsson T, Huang P, Jonckheere L, et al.
J Exp Med . 2025 Mar; 222(5). PMID: 40029331
Ataxia telangiectasia and Rad3-related (ATR) kinase and its interacting protein ATRIP orchestrate the replication stress response. Homozygous splice variants in the ATRIP gene, resulting in ATRIP deficiency, were identified in...
2.
Hoste L, Meertens B, Ogunjimi B, Sabato V, Guerti K, van der Hilst J, et al.
Inflammation . 2024 Nov; PMID: 39528768
Patients with non-infectious systemic inflammation may suffer from one of many diseases, including hyperinflammation (HI), autoinflammatory disorders (AID), and systemic autoimmune disease (AI). Despite their clinical overlap, the pathophysiology and...
3.
Buytaert M, Kaddouri R, Hoste L, Meertens B, Tavernier S, Claes K, et al.
J Interferon Cytokine Res . 2024 Jun; 44(8):372-378. PMID: 38934089
The study of sensitive and specific biomarkers, such as blood inflammatory cytokines, could provide an answer to the challenges faced in the differential diagnosis of patients with systemic inflammation. Limited...
4.
Naesens L, Muppala S, Acharya D, Nemegeer J, Bogaert D, Lee J, et al.
Sci Immunol . 2022 Nov; 7(77):eabq4531. PMID: 36399538
Herpes simplex virus 1 (HSV-1) infects several billion people worldwide and can cause life-threatening herpes simplex encephalitis (HSE) in some patients. Monogenic defects in components of the type I interferon...
5.
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, et al.
J Exp Med . 2021 Dec; 219(2). PMID: 34914824
In rare instances, pediatric SARS-CoV-2 infection results in a novel immunodysregulation syndrome termed multisystem inflammatory syndrome in children (MIS-C). We compared MIS-C immunopathology with severe COVID-19 in adults. MIS-C does...
6.
Bogaert D, De Bruyne M, Debacker V, Depuydt P, De Preter K, Bonroy C, et al.
Haematologica . 2016 Sep; 102(1):192-202. PMID: 27634199
The etiology of primary antibody deficiencies is largely unknown. Beside rare monogenic forms, the majority of cases seem to have a more complex genetic basis. Whereas common variable immunodeficiency has...
7.
Van Den Broeck T, Stevenaert F, Taveirne S, Debacker V, Vangestel C, Vandekerckhove B, et al.
Blood . 2008 Sep; 112(13):5046-51. PMID: 18784372
The Ly49 natural killer (NK)-cell receptor family comprises both activating and inhibitory members, which recognize major histocompatibility complex (MHC) class I or MHC class I-related molecules and are involved in...
8.
Stevenaert F, Van Beneden K, De Colvenaer V, Franki A, Debacker V, Boterberg T, et al.
Blood . 2005 Apr; 106(3):956-62. PMID: 15827137
A crucial step in murine natural killer (NK) cell development, mediated by bone marrow stromal cells, is the induction of Ly49 and CD94/NKG2 receptor expression. The signals that regulate Ly49...
9.
Claerhout I, Kestelyn P, Debacker V, Beele H, Leclercq G
Transplantation . 2004 Mar; 77(5):676-82. PMID: 15021828
Background: The exact mechanism of human corneal allograft rejection, which is the major cause of corneal transplant failure, remains unclear. We investigated the role of natural killer (NK) cells in...
10.
Stevenaert F, Van Beneden K, De Creus A, Debacker V, Plum J, Leclercq G
J Leukoc Biol . 2003 May; 73(6):731-8. PMID: 12773505
Using a new antibody, we found previously that contrary to adult natural killer (NK) cells, fetal NK cells have a unique phenotype, as they exclusively express Ly49E. This can be...