Valery L Payen
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Explore the profile of Valery L Payen including associated specialties, affiliations and a list of published articles.
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22
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1422
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Recent Articles
11.
Milosevic T, Payen V, Sonveaux P, Muccioli G, Tulkens P, Van Bambeke F
Antimicrob Agents Chemother
. 2017 Dec;
62(3).
PMID: 29263063
Linezolid, the first clinically available oxazolidinone antibiotic, causes potentially severe toxicities (myelosuppression, lactic acidosis, and neuropathies) ascribed to impairment of mitochondrial protein synthesis and consecutive mitochondrial dysfunction. Tedizolid, a newly...
12.
(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice
Payen V, Porporato P, Danhier P, Vazeille T, Blackman M, May B, et al.
Front Pharmacol
. 2017 Dec;
8:869.
PMID: 29255416
Metastasis is of dismal prognosis for cancer patients, but recent evidence in mouse models of cancer shows that metastasis prevention is a reachable clinical objective. These experiments indicate that altered...
13.
Payen V, Hsu M, Radecke K, Wyart E, Vazeille T, Bouzin C, et al.
Cancer Res
. 2017 Aug;
77(20):5591-5601.
PMID: 28827372
Extracellular acidosis resulting from intense metabolic activities in tumors promotes cancer cell migration, invasion, and metastasis. Although host cells die at low extracellular pH, cancer cells resist, as they are...
14.
Danhier P, Banski P, Payen V, Grasso D, Ippolito L, Sonveaux P, et al.
Biochim Biophys Acta Bioenerg
. 2017 Feb;
1858(8):556-572.
PMID: 28167100
Altered metabolism in cancer cells is pivotal for tumor growth, most notably by providing energy, reducing equivalents and building blocks while several metabolites exert a signaling function promoting tumor growth...
15.
Perez-Escuredo J, Van Hee V, Sboarina M, Falces J, Payen V, Pellerin L, et al.
Biochim Biophys Acta
. 2016 Mar;
1863(10):2481-97.
PMID: 26993058
Monocarboxylate transporters (MCTs) constitute a family of 14 members among which MCT1-4 facilitate the passive transport of monocarboxylates such as lactate, pyruvate and ketone bodies together with protons across cell...
16.
De Preter G, Danhier P, Porporato P, Payen V, Jordan B, Sonveaux P, et al.
Adv Exp Med Biol
. 2016 Jan;
876:209-214.
PMID: 26782214
The aim of the study was to assess the link between the metabolic profile and the proliferation capacity of a range of human and murine cancer cell lines. First, the...
17.
Porporato P, Payen V, Baselet B, Sonveaux P
Cell Mol Life Sci
. 2015 Dec;
73(7):1349-63.
PMID: 26646069
Metabolic alterations are a hallmark of cancer controlling tumor progression and metastasis. Among the various metabolic phenotypes encountered in tumors, this review focuses on the contributions of mitochondria, lipid and...
18.
Payen V, Porporato P, Baselet B, Sonveaux P
Cell Mol Life Sci
. 2015 Dec;
73(7):1333-48.
PMID: 26626411
Metabolic adaptations are intimately associated with changes in cell behavior. Cancers are characterized by a high metabolic plasticity resulting from mutations and the selection of metabolic phenotypes conferring growth and...
19.
De Preter G, Neveu M, Danhier P, Brisson L, Payen V, Porporato P, et al.
Oncotarget
. 2015 Nov;
7(3):2910-20.
PMID: 26543237
Glucose fermentation through glycolysis even in the presence of oxygen (Warburg effect) is a common feature of cancer cells increasingly considered as an enticing target in clinical development. This study...
20.
Payen V, Brisson L, Dewhirst M, Sonveaux P
Cancer J
. 2015 Mar;
21(2):75-87.
PMID: 25815847
Hypoxia is a characteristic of tumors and wounds. Hypoxic cells develop 2 common strategies to face hypoxia: the glycolytic switch and the angiogenic switch. At the onset of hypoxia, alleviation...