Valeria Napolitano
Overview
Explore the profile of Valeria Napolitano including associated specialties, affiliations and a list of published articles.
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23
Citations
114
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Recent Articles
1.
Romano M, Falchi F, De Gregorio E, Stabile M, Migliaccio A, Ruggiero A, et al.
Front Microbiol
. 2024 Dec;
15:1501051.
PMID: 39669780
Introduction: Antimicrobial-resistant pathogens are an ongoing threat to human and animal health. According to the World Health Organization (WHO), colistin is considered the last resort antibiotic against human infections due...
2.
Banasik M, Napolitano V, Blat A, Abdulkarim K, Plewka J, Czaplewski C, et al.
Int J Biol Macromol
. 2024 Sep;
280(Pt 4):135510.
PMID: 39304044
Peroxisomal protein import has been identified as a valid target in trypanosomiases, an important health threat in Central and South America. The importomer is built of multiple peroxins (Pex) and...
3.
Kramarska E, Toumi E, Squeglia F, Laverde D, Napolitano V, Frapy E, et al.
NPJ Vaccines
. 2024 Aug;
9(1):151.
PMID: 39155280
ESKAPE pathogens are responsible for complicated nosocomial infections worldwide and are often resistant to commonly used antibiotics in clinical settings. Among ESKAPE, vancomycin-resistant Enterococcus faecium (VREfm) and methicillin-resistant Staphylococcus aureus...
4.
Vestuto V, Ciaglia T, Musella S, Di Sarno V, Smaldone G, Di Matteo F, et al.
J Med Chem
. 2024 Jul;
67(15):12711-12734.
PMID: 39038808
Haspin is an emerging, but rather unexplored, divergent kinase involved in tumor growth by regulating the mitotic phase. In this paper, the design, synthesis, and biological characterization of a new...
5.
Berisio R, Barra G, Napolitano V, Privitera M, Romano M, Squeglia F, et al.
Biomolecules
. 2024 Apr;
14(4).
PMID: 38672487
Tuberculosis (TB) is the leading global cause of death f rom an infectious bacterial agent. Therefore, limiting its epidemic spread is a pressing global health priority. The chaperone-like protein HtpG...
6.
Ciaglia T, Vestuto V, Di Sarno V, Musella S, Smaldone G, Di Matteo F, et al.
Eur J Med Chem
. 2024 Jan;
266:116128.
PMID: 38232463
In this paper we present the design, synthesis, and biological evaluation of a new series of peptidomimetics acting as potent anti-SARS-CoV-2 agents. Starting from our previously described Main Protease (M)...
7.
Troisi R, Napolitano V, Rossitto E, Osman W, Nagano M, Wakui K, et al.
Nucleic Acids Res
. 2023 Jul;
51(16):8880-8890.
PMID: 37503836
Ligand/protein molecular recognition involves a dynamic process, whereby both partners require a degree of structural plasticity to regulate the binding/unbinding event. Here, we present the characterization of the interaction between...
8.
Marciniak M, Mroz P, Napolitano V, Kalel V, Fino R, Pykacz E, et al.
Eur J Med Chem
. 2023 Jul;
258:115587.
PMID: 37406382
Protein-protein interactions (PPIs) constitute an important but challenging class of molecular targets for small molecules. The PEX5-PEX14 PPI has been shown to play a critical role in glycosome biogenesis and...
9.
Musella S, DAvino D, Peltner L, Di Sarno V, Cerqua I, Merciai F, et al.
J Med Chem
. 2023 Jun;
66(13):9201-9222.
PMID: 37334504
Acute pancreatitis (AP) is a potentially life-threatening illness characterized by an exacerbated inflammatory response with limited options for pharmacological treatment. Here, we describe the rational development of a library of...
10.
Magoch M, McEwen A, Napolitano V, Wladyka B, Dubin G
Molecules
. 2023 Jun;
28(11).
PMID: 37298883
is a common opportunistic pathogen of humans and livestock that causes a wide variety of infections. The success of as a pathogen depends on the production of an array of...