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Valeria Castelletto

Explore the profile of Valeria Castelletto including associated specialties, affiliations and a list of published articles. Areas
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Articles 125
Citations 970
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Recent Articles
1.
Adak A, Castelletto V, de Mello L, Mendes B, Barrett G, Seitsonen J, et al.
ACS Appl Bio Mater . 2025 Feb; PMID: 39918396
No abstract available.
2.
de Mello L, Castelletto V, Cavalcanti L, Seitsonen J, Hamley I
J Pept Sci . 2025 Feb; 31(3):e70002. PMID: 39904960
Lipoic acid is a biocompatible compound with antioxidant activity that is of considerable interest in cosmetic formulations, and the disulfide group in the N-terminal ring confers redox activity. Here, we...
3.
Adak A, Castelletto V, de Mello L, Mendes B, Barrett G, Seitsonen J, et al.
ACS Appl Bio Mater . 2025 Jan; 8(1):803-813. PMID: 39792083
A series of tripodal (three-arm) lysine-based peptides were designed and synthesized and their self-assembly properties in aqueous solution and antimicrobial activity were investigated. We compare the behaviors of homochiral tripodal...
4.
Castelletto V, de Mello L, Seitsonen J, Hamley I
ACS Appl Mater Interfaces . 2024 Dec; 16(50):68713-68723. PMID: 39651938
Short bioactive peptide sequences are of great interest in biomaterials development. We investigate the self-assembly of a lipopeptide containing both the highly cationic CSK toll-like receptor agonist hexapeptide sequence and...
5.
Castelletto V, Seitsonen J, de Mello L, Hamley I
Biomacromolecules . 2024 Oct; 25(11):7410-7420. PMID: 39469728
The interaction of the surfactant-like peptide (SLP) RL bearing three cationic arginine residues with model liposomes is investigated in aqueous solution at various pH values, under conditions for which the...
6.
Adak A, Castelletto V, Hamley I, Seitsonen J, Jana A, Ghosh S, et al.
ACS Appl Mater Interfaces . 2024 Oct; 16(43):58417-58426. PMID: 39422705
The self-assembly of lipopeptide (peptide amphiphile) molecules bearing single linear lipid chains has been widely studied, as has their diverse range of bioactivities. Here, we introduce lipopeptides bearing one or...
7.
Hamley I, Castelletto V
ACS Polym Au . 2024 Aug; 4(4):266-272. PMID: 39156559
We examine the effect of alpha-cyclodextrin (αCD) on the crystallization of poly(ethylene glycol) (PEG) [poly(ethylene oxide), PEO] in low-molar-mass polymers, with = 1000, 3000, or 6000 g mol. Differential scanning...
8.
Hamley I, Adak A, Castelletto V
Nat Commun . 2024 Aug; 15(1):6785. PMID: 39117639
Lipopeptides can self-assemble into diverse nanostructures which can be programmed to incorporate peptide sequences to achieve a remarkable range of bioactivities. Here, the influence of peptide sequence and chirality on...
9.
Castelletto V, Seitsonen J, Pollitt A, Hamley I
Biomacromolecules . 2024 Jul; 25(8):5321-5331. PMID: 39066731
The simple (self-)coacervation of the minimal tryptophan/arginine peptide sequences WR and WR was observed in salt-free aqueous solution. The phase diagrams were mapped using turbidimetry and optical microscopy, and the...
10.
Adak A, Castelletto V, Mendes B, Barrett G, Seitsonen J, Hamley I
ACS Appl Bio Mater . 2024 Jul; 7(8):5553-5565. PMID: 39042039
Chirality plays a crucial role in the self-assembly of biomolecules in nature. Peptides show chirality-dependent conformation and self-assembly. Lipidation of peptides occurs in vivo and has recently been exploited in...