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Steven Kirkham

Explore the profile of Steven Kirkham including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 94
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Recent Articles
1.
Nandi N, Gayen K, Ghosh S, Bhunia D, Kirkham S, Sen S, et al.
Biomacromolecules . 2017 Sep; 18(11):3621-3629. PMID: 28953367
A series of peptides with a long fatty acyl chain covalently attached to the C-terminal part and a free amine (-NH) group at the N-terminus have been designed so that...
2.
Nandi N, Basak S, Kirkham S, Hamley I, Banerjee A
Langmuir . 2016 Dec; 32(49):13226-13233. PMID: 27951681
Two-component fluorescent hydrogels have been discovered, containing the mixtures of naphthalene diimide (NDI)-conjugated peptide-functionalized bola-amphiphile and primary amines with long alkyl chains at physiological pH 7.46. The aggregation-induced enhanced emission...
3.
Hamley I, Hutchinson J, Kirkham S, Castelletto V, Kaur A, Reza M, et al.
Langmuir . 2016 Sep; 32(40):10387-10393. PMID: 27636825
The surfactant-like peptide (Ala)-(Asp) (AD) is shown to self-assemble into ultrathin (3 nm thick) nanosheets in aqueous solution above a critical aggregation concentration. A combination of circular dichroism and FTIR...
4.
Kirkham S, Castelletto V, Hamley I, Inoue K, Rambo R, Reza M, et al.
Chemphyschem . 2016 Apr; 17(14):2118-22. PMID: 27043447
The cyclic lipopeptide Daptomycin, used as a treatment for infections where antimicrobial resistance is observed, is shown to self-assemble into spherical micelles above a critical aggregation concentration. Micelles are observed...
5.
Kirkham S, Castelletto V, Hamley I, Reza M, Ruokolainen J, Hermida-Merino D, et al.
Biomacromolecules . 2016 Feb; 17(3):1186-97. PMID: 26867986
The self-assembly in aqueous solution of three novel telechelic conjugates comprising a central hydrophilic polymer and short (trimeric or pentameric) tyrosine end-caps has been investigated. Two of the conjugates have...
6.
Castelletto V, Kirkham S, Hamley I, Kowalczyk R, Rabe M, Reza M, et al.
Biomacromolecules . 2016 Jan; 17(2):631-40. PMID: 26752598
The self-assembly of the macrophage-activating lipopeptide MALP-2 in aqueous solution has been investigated and is compared to that of the constituent peptide GNNDESNISFKEK. MALP-2 is a toll-like receptor agonist lipopeptide...
7.
Hamley I, Kirkham S, Kowalczyk R, Castelletto V, Reza M, Ruokolainen J
Chem Commun (Camb) . 2015 Dec; 52(5):1052. PMID: 26687772
Correction for 'Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes' by Ian William Hamley et al., Chem. Commun., 2015, 51, 17680-17683.
8.
Hamley I, Kirkham S, Kowalczyk R, Castelletto V, Reza M, Ruokolainen J
Chem Commun (Camb) . 2015 Oct; 51(100):17680-3. PMID: 26499063
The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic...
9.
Kirkham S, Hamley I, Smith A, Gouveia R, Connon C, Reza M, et al.
Colloids Surf B Biointerfaces . 2015 May; 137:104-8. PMID: 25990811
Derivatives of fluorophore FITC (fluorescein isothiocyanate) are widely used in bioassays to label proteins and cells. An N-terminal leucine dipeptide is attached to FITC, and we show that this simple...
10.
Hamley I, Kirkham S, Dehsorkhi A, Castelletto V, Reza M, Ruokolainen J
Chem Commun (Camb) . 2014 Nov; 50(100):15948-51. PMID: 25382300
The self-assembled structure of toll-like receptor agonist lipopeptides containing the CSK4 peptide sequence is examined in aqueous solution. A remarkable dependence of morphology on the number of attached hexadecyl lipid...