Emerson Rodrigo da Silva
Overview
Explore the profile of Emerson Rodrigo da Silva including associated specialties, affiliations and a list of published articles.
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15
Citations
38
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Recent Articles
1.
Castelletto V, de Mello L, da Silva E, Seitsonen J, Hamley I
J Pept Sci
. 2024 Feb;
30(6):e3571.
PMID: 38374800
The self-assembly in aqueous solution of three Fmoc-amino acids with hydrophobic (aliphatic or aromatic, alanine or phenylalanine) or hydrophilic cationic residues (arginine) is compared. The critical aggregation concentrations were obtained...
2.
Bicev R, Degenhardt M, Oliveira C, da Silva E, Degrouard J, Tresset G, et al.
Sci Rep
. 2023 Nov;
13(1):19383.
PMID: 37938622
Caloric restriction is known to extend the lifespan and/or improve diverse physiological parameters in a vast array of organisms. In the yeast Saccharomyces cerevisiae, caloric restriction is performed by reducing...
3.
Castelletto V, de Mello L, da Silva E, Seitsonen J, Hamley I
Biomacromolecules
. 2023 Nov;
24(11):5403-5413.
PMID: 37914531
There has been considerable interest in peptides in which the Fmoc (9-fluorenylmethoxycarbonyl) protecting group is retained at the N-terminus, since this bulky aromatic group can drive self-assembly, and Fmoc-peptides are...
4.
Porosk L, Hark H, Bicev R, Gaidutsik I, Nebogatova J, Armolik E, et al.
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36901707
Alzheimer's disease (AD) is the most common neurodegenerative disease (ND) and the leading cause of dementia. It is characterized by non-linear, genetic-driven pathophysiological dynamics with high heterogeneity in the biological...
5.
Methods for Small-Angle Scattering Measurements on Peptiplexes of DNA with Cell-Penetrating Peptides
da Silva E, Mello L, Hamley I
Methods Mol Biol
. 2021 Nov;
2383:181-196.
PMID: 34766290
Peptiplexes are soft biomaterials formed through the noncovalent association between cell-penetrating peptides and nucleic acids. Although internalization often involves electrostatic anchoring followed by endocytosis, the mode of action of these...
6.
Cinel V, Taketa T, de Carvalho B, de la Torre L, Mello L, da Silva E, et al.
Biopolymers
. 2021 May;
112(7):e23432.
PMID: 33982812
Efficient delivery of nanometric vectors complexed with nanoparticles at a target tissue without spreading to other tissues is one of the main challenges in gene therapy. One means to overcome...
7.
Castelletto V, Edwards-Gayle C, Hamley I, Barrett G, Seitsonen J, Ruokolainen J, et al.
Chem Commun (Camb)
. 2019 Dec;
56(4):615-618.
PMID: 31833497
Three model arginine-rich tripeptides RXR (X = W, F or non-natural residue 2-napthylalanine) were investigated as antimicrobial agents, with a specific focus to target Pseudomonas aeruginosa through membrane lysis. Activity...
8.
Mello L, Hamley I, Castelletto V, Garcia B, Han S, Oliveira C, et al.
J Phys Chem B
. 2019 Aug;
123(42):8861-8871.
PMID: 31465229
One of the most remarkable examples of cell-penetrating peptides (CPPs) is , a 16-mer fragment derived from the homeobox. Understanding the structure of /DNA complexes is a key factor for...
9.
Gerbelli B, da Silva E, Miranda Soares B, Alves W, Andreoli de Oliveira E
Langmuir
. 2017 Dec;
34(5):2171-2179.
PMID: 29284081
In the present work, we investigate the effect of two short phenylalanine-based peptides on lipid membranes. A simplified model membrane composed of lecithin vesicles was used to incorporate different amounts...
10.
Hamley I, Burholt S, Hutchinson J, Castelletto V, da Silva E, Alves W, et al.
Biomacromolecules
. 2017 Apr;
18(5):1660.
PMID: 28394583
No abstract available.