V E Marquez
Overview
Explore the profile of V E Marquez including associated specialties, affiliations and a list of published articles.
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Articles
126
Citations
1453
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Recent Articles
1.
Fulkerson C, Dhawan D, Jones D, Marquez V, Jones P, Wang Z, et al.
Vet Comp Oncol
. 2015 Jul;
15(1):226-236.
PMID: 26178438
The purpose of this study was to determine the plasma pharmacokinetics (PK) and toxicity of zebularine, an oral cytidine analog with demethylating activity, in dogs. Plasma zebularine concentrations were determined...
2.
Ciarapica R, De Salvo M, Carcarino E, Bracaglia G, Adesso L, Leoncini P, et al.
Oncogene
. 2013 Nov;
33(32):4173-84.
PMID: 24213577
The Polycomb group (PcG) proteins regulate stem cell differentiation via the repression of gene transcription, and their deregulation has been widely implicated in cancer development. The PcG protein Enhancer of...
3.
Zhao X, Lwin T, Zhang X, Huang A, Wang J, Marquez V, et al.
Leukemia
. 2013 Mar;
27(12):2341-50.
PMID: 23538750
c-MYC (hereafter MYC) overexpression has been recognized in aggressive B-cell lymphomas and linked to adverse prognosis. MYC activation results in widespread repression of micro-RNA (miRNA) expression and associated with lymphoma...
4.
Taniguchi H, Jacinto F, Villanueva A, Fernandez A, Yamamoto H, Carmona F, et al.
Oncogene
. 2011 Sep;
31(15):1988-94.
PMID: 21892211
The Kruppel-like factor (KLF) proteins are multitasked transcriptional regulators with an expanding tumor suppressor function. KLF2 is one of the prominent members of the family because of its diminished expression...
5.
Stumpel D, Schotte D, Lange-Turenhout E, Schneider P, Seslija L, de Menezes R, et al.
Leukemia
. 2010 Dec;
25(3):429-39.
PMID: 21116279
MLL-rearranged acute lymphoblastic leukemia (ALL) in infants (<1 year) is the most aggressive type of childhood leukemia. To develop more suitable treatment strategies, a firm understanding of the biology underlying...
6.
McCormack J, Marquez V, Liu P, Vistica D, Driscoll J
Biochem Pharmacol
. 2010 Mar;
29(5):830-2.
PMID: 20227965
No abstract available.
7.
Blumberg P, Kedei N, Lewin N, Yang D, Czifra G, Pu Y, et al.
Curr Drug Targets
. 2008 Aug;
9(8):641-52.
PMID: 18691011
The diacylglycerol-responsive C1 domains of protein kinase C and of the related classes of signaling proteins represent highly attractive targets for drug development. The signaling functions that are regulated by...
8.
Vives M, Eritja R, Tauler R, Marquez V, Gargallo R
Biopolymers
. 2003 Dec;
73(1):27-43.
PMID: 14691937
The nucleoside 2'-deoxyzebularine (K) was incorporated into the self-complementary dodecamer 5'-CGTACGKGTACG-3' by solid-phase 2-cyanoethylphosphoramidite chemistry using dimethoxytrityl (DMT) as the 5'-hydroxyl protecting group. Standard synthesis cycles using trichloroacetic acid and...
9.
Guimil Garcia R, Brank A, Christman J, Marquez V, Eritja R
Antisense Nucleic Acid Drug Dev
. 2002 Feb;
11(6):369-78.
PMID: 11838638
The incorporation of 5-azacytosine residues into DNA causes potent inhibition of DNA (Cytosine-C5) methyltransferases. The synthesis of oligodeoxyribonucleotides incorporating single or multiple 5-aza-2'-deoxycytidine residues at precise sites was undertaken to...
10.
Lee J, Han K, Kang J, Pearce L, Lewin N, Yan S, et al.
J Med Chem
. 2001 Dec;
44(25):4309-12.
PMID: 11728178
An approach to reduce the log P in a series of diacylglycerol (DAG)-lactones known for their high binding affinity for protein kinase C (PK-C) is presented. Branched alkyl groups with...