V A Letts
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Explore the profile of V A Letts including associated specialties, affiliations and a list of published articles.
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19
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943
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Recent Articles
1.
Letts V, Beyer B, Frankel W
Genes Brain Behav
. 2014 May;
13(6):519-26.
PMID: 24861780
Twenty-seven inbred strains of mice were tested for spike-wave discharge (SWD) activity by video-electroencephalographic recordings over a 24-h recording period. Eight strains had reproducible, frequent SWDs, including five strains (C57BLKS/J,...
2.
Miki T, Zwingman T, Wakamori M, Lutz C, Cook S, Hosford D, et al.
Neuroscience
. 2008 Jul;
155(1):31-44.
PMID: 18597946
The calcium channel CACNA1A gene encodes the pore-forming, voltage-sensitive subunit of the voltage-dependent calcium Ca(v)2.1 type channel. Mutations in this gene have been linked to several human disorders, including familial...
3.
Barclay J, Balaguero N, Mione M, Ackerman S, Letts V, Brodbeck J, et al.
J Neurosci
. 2001 Aug;
21(16):6095-104.
PMID: 11487633
The mouse mutant ducky, a model for absence epilepsy, is characterized by spike-wave seizures and ataxia. The ducky gene was mapped previously to distal mouse chromosome 9. High-resolution genetic and...
4.
Kang M, Chen C, Felix R, Letts V, Frankel W, Mori Y, et al.
J Biol Chem
. 2001 Jul;
276(35):32917-24.
PMID: 11441000
A novel gene (Cacng2; gamma(2)) encoding a protein similar to the voltage-activated Ca(2+) channel gamma(1) subunit was identified as the defective gene in the epileptic and ataxic mouse, stargazer. In...
5.
Cox G, Mahaffey C, Nystuen A, Letts V, Frankel W
Nat Genet
. 2000 Oct;
26(2):198-202.
PMID: 11017077
The mouse mutation fidget arose spontaneously in a heterogeneous albino stock. This mutant mouse is characterized by a side-to-side head-shaking and circling behaviour, due to reduced or absent semicircular canals....
6.
Letts V, Valenzuela A, Dunbar C, Zheng Q, Johnson K, Frankel W
Mamm Genome
. 2000 Sep;
11(10):831-5.
PMID: 11003695
A new mouse mutant, punk rocker (allele symbol Kcne1(pkr)), arose spontaneously on a C57BL/10J inbred strain background and is characterized by a distinctive head-tossing, circling, and ataxic phenotype. It is...
7.
Letts V, Felix R, Biddlecome G, Arikkath J, Mahaffey C, Valenzuela A, et al.
Nat Genet
. 1998 Aug;
19(4):340-7.
PMID: 9697694
Stargazer mice have spike-wave seizures characteristic of absence epilepsy, with accompanying defects in the cerebellum and inner ear. We describe here a novel gene, Cacng2, whose expression is disrupted in...
8.
Letts V, Valenzuela A, Kirley J, Sweet H, Davisson M, Frankel W
Genomics
. 1997 Jul;
43(1):62-8.
PMID: 9226373
The stargazer mouse mutation causes absence seizures that are more prolonged and frequent than any other petit mal mouse model. Stargazer mice also have an ataxic gait and vestibular problems,...
9.
Letts V, Schork N, Copp A, Bernfield M, Frankel W
Genomics
. 1995 Oct;
29(3):719-24.
PMID: 8575765
The major gene for neural tube defects, ct, in the curly-tail (CT) mouse strain was mapped previously to mouse chromosome 4 by combining linkage data from several backcrosses. The penetrance...
10.
Hasenkrug K, Valenzuela A, Letts V, Nishio J, Chesebro B, Frankel W
J Virol
. 1995 Apr;
69(4):2617-20.
PMID: 7884913
Inoculation of adult mice with Friend virus complex usually induces rapid viremia and erythroleukemia, resulting in death in 1 to 3 months. In certain mouse strains, a single host gene,...