I W Dawes
Overview
Explore the profile of I W Dawes including associated specialties, affiliations and a list of published articles.
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Articles
93
Citations
1701
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Recent Articles
1.
Grant C, Dawes I
Redox Rep
. 2016 Jul;
2(4):223-9.
PMID: 27406271
Glutathione (GSH) is an abundant and ubiquitous low-molecular-mass thiol with proposed roles in many cellular processes including amino acid transport, synthesis of proteins and nucleic acids, modulation of enzyme activity...
2.
Nair S, Traini M, Dawes I, Perrone G
Mol Biol Cell
. 2014 May;
25(15):2235-49.
PMID: 24870034
Amyloid-β (Aβ)-containing plaques are a major neuropathological feature of Alzheimer's disease (AD). The two major isoforms of Aβ peptide associated with AD are Aβ40 and Aβ42, of which the latter...
3.
Lee J, Straffon M, Jang T, Higgins V, Grant C, Dawes I
FEMS Yeast Res
. 2003 Apr;
1(1):57-65.
PMID: 12702463
A grande gsh1 disruptant mutant of Saccharomyces cerevisiae was generated by crossing a petite disruptant to a wild-type grande strain. This strain was relatively stable, but generated petites at an...
4.
Tait A, Cranmer S, Jackson S, Dawes I, Chong B
Blood
. 2001 Sep;
98(6):1812-8.
PMID: 11535515
To maintain hemostasis under shear conditions, there must be an interaction between the platelet glycoprotein (GP) Ib-IX receptor and the plasma ligand von Willebrand factor (vWf). In platelet-type von Willebrand...
5.
Higgins V, Bell P, Dawes I, Attfield P
Appl Environ Microbiol
. 2001 Aug;
67(9):4346-8.
PMID: 11526044
A yeast strain capable of leavening both unsugared and sweet bread dough efficiently would reduce the necessity of carrying out the expensive procedure of producing multiple baker's yeast strains. But...
6.
Alic N, Higgins V, Dawes I
Mol Biol Cell
. 2001 Jun;
12(6):1801-10.
PMID: 11408586
Reactive oxygen species cause damage to all of the major cellular constituents, including peroxidation of lipids. Previous studies have revealed that oxidative stress, including exposure to oxidation products, affects the...
7.
Collins B, Harrop S, Kornfeld G, Dawes I, Curmi P, Mabbutt B
J Mol Biol
. 2001 Jun;
309(4):915-23.
PMID: 11399068
The Sm/Lsm proteins associate with small nuclear RNA to form the core of small nuclear ribonucleoproteins, required for processes as diverse as pre-mRNA splicing, mRNA degradation and telomere formation. The...
8.
Gurvitz A, Wabnegger L, Rottensteiner H, Dawes I, Hartig A, Ruis H, et al.
Mol Cell Biol Res Commun
. 2001 Feb;
4(2):81-9.
PMID: 11170837
The role of Saccharomyces cerevisiae Adr1p was examined with respect to the transcriptional regulation of the SPS19 gene encoding the peroxisomal beta-oxidation auxiliary enzyme 2,4-dienoyl-CoA reductase. The SPS19 promoter contains...
9.
Piper M, Hong S, Ball G, Dawes I
J Biol Chem
. 2000 Jun;
275(40):30987-95.
PMID: 10871621
One-carbon metabolism in yeast is an essential process that relies on at least one of three one-carbon donor molecules: serine, glycine, or formate. By a combination of genetics and biochemistry...
10.
Draculic T, Dawes I, Grant C
Mol Microbiol
. 2000 Jun;
36(5):1167-74.
PMID: 10844700
Glutaredoxins and thioredoxins are small heat-stable oxidoreductases that have been conserved throughout evolution. The yeast Saccharomyces cerevisiae contains two gene pairs encoding cytoplasmic glutaredoxins (GRX1, GRX2) and thioredoxins (TRX1, TRX2)....