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Utpal P Dave

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Articles 29
Citations 470
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Recent Articles
1.
Hardwick J, Rodriguez-Hernaez J, Gambi G, Venters B, Guo Y, Li L, et al.
J Biol Chem . 2025 Jan; 301(3):108233. PMID: 39880094
The Hhex gene encodes a transcription factor that is important for both embryonic and post-natal development, especially of hematopoietic tissues. Hhex is one of the most common sites of retroviral...
2.
Dave U, Bungert J
Mol Ther . 2024 Sep; 32(10):3197-3198. PMID: 39293432
No abstract available.
3.
Marino S, Petrusca D, Bishop R, Anderson J, Sabol H, Ashby C, et al.
Haematologica . 2023 Nov; 109(5):1501-1513. PMID: 37981834
Multiple myeloma (MM) is a malignancy of plasma cells whose antibody secretion creates proteotoxic stress relieved by the N-end rule pathway, a proteolytic system that degrades N-arginylated proteins in the...
4.
Pasupuleti S, Ramdas B, Burns S, Palam L, Kanumuri R, Kumar R, et al.
J Clin Invest . 2023 Apr; 133(11). PMID: 37071471
Characterized by the accumulation of somatic mutations in blood cell lineages, clonal hematopoiesis of indeterminate potential (CHIP) is frequent in aging and involves the expansion of mutated hematopoietic stem and...
5.
Palam L, Ramdas B, Pickerell K, Pasupuleti S, Kanumuri R, Cesarano A, et al.
JCI Insight . 2023 Mar; 8(9). PMID: 36976647
Loss-of-function mutations in the DNA methyltransferase 3A (DNMT3A) are seen in a large number of patients with acute myeloid leukemia (AML) with normal cytogenetics and are frequently associated with poor...
6.
Atallah-Yunes S, Robertson M, Dave U, Ghione P, Perna F
Front Immunol . 2022 Jun; 13:901365. PMID: 35720352
Prognosis for patients with refractory/relapsed (R/R) diffuse large B-cell lymphoma (DLBCL) is poor. Immune-based therapeutic treatments such as CD19 Chimeric Antigen Receptor (CAR) T cell therapies have dramatically changed the...
7.
Atallah-Yunes S, Robertson M, Dave U
Clin Lymphoma Myeloma Leuk . 2022 May; 22(9):659-665. PMID: 35577752
Peripheral T cell lymphomas (PTCL) comprise a diverse group of aggressive T-cell and NK-cell lymphomas with many subtypes sharing same treatment algorithms despite having different pathobiology and responses to treatment....
8.
Dave U, Cornetta K
Mol Ther . 2021 Jan; 29(2):418-419. PMID: 33472035
No abstract available.
9.
Roels J, Thenoz M, Szarzynska B, Landfors M, De Coninck S, Demoen L, et al.
Blood Cancer Discov . 2020 Nov; 1(3):274-289. PMID: 33179015
Cancer cells display DNA hypermethylation at specific CpG islands in comparison to their normal healthy counterparts, but the mechanism that drives this so-called CpG island methylator phenotype (CIMP) remains poorly...
10.
Wu X, Niculite C, Preda M, Rossi A, Tebaldi T, Butoi E, et al.
Nat Commun . 2020 Nov; 11(1):5737. PMID: 33159065
An amendment to this paper has been published and can be accessed via a link at the top of the paper.