Ursula Greferath
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Explore the profile of Ursula Greferath including associated specialties, affiliations and a list of published articles.
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46
Citations
606
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Recent Articles
1.
Jobling A, Greferath U, Dixon M, Quiriconi P, Eyar B, van Koeverden A, et al.
Prog Retin Eye Res
. 2025 Feb;
106:101349.
PMID: 40020909
The high metabolic demand of retinal neurons requires a precisely regulated vascular system that can deliver rapid changes in blood flow in response to neural need. In the retina, this...
2.
Masri R, Greferath U, Fletcher E, Martin P, Grunert U
Invest Ophthalmol Vis Sci
. 2025 Feb;
66(2):46.
PMID: 39964323
Purpose: Previous evidence indicates that molecular properties of foveal Müller cells are different from those in the peripheral retina. Here we aimed to characterize Müller cells in the human fovea...
3.
Lee P, Greferath U, Zhao D, Huang J, Wang A, Vessey K, et al.
Optom Vis Sci
. 2025 Jan;
102(2):78-89.
PMID: 39882862
Significance: Previous evidence showed that transient receptor potential vanilloid 4 (TRPV4) inhibition was protective of retinal ganglion cell (RGC) loss after chronic intraocular pressure (IOP) elevation in young animals. However,...
4.
Liu J, Copland D, Clare A, Gorski M, Richards B, Scott L, et al.
Sci Transl Med
. 2024 Jun;
16(750):eadi4125.
PMID: 38838135
Chronic inflammation is a constitutive component of many age-related diseases, including age-related macular degeneration (AMD). Here, we identified interleukin-1 receptor-associated kinase M (IRAK-M) as a key immunoregulator in retinal pigment...
5.
Vessey K, Jobling A, Greferath U, Fletcher E
Curr Opin Pharmacol
. 2024 May;
76:102463.
PMID: 38788268
Age-related macular degeneration (AMD) is a major cause of irreversible vision loss in the elderly. Although new therapies have recently emerged, there are currently no ways of preventing the development...
6.
Liu J, Copland D, Clare A, Gorski M, Richards B, Scott L, et al.
bioRxiv
. 2023 Oct;
PMID: 37808640
Unchecked, chronic inflammation is a constitutive component of age-related diseases, including age-related macular degeneration (AMD). Here we identified interleukin-1 receptor-associated kinase (IRAK)-M as a key immunoregulator in retinal pigment epithelium...
7.
Greferath U, Fletcher E, Savige J, Mack H
Am J Ophthalmol
. 2023 Sep;
257:247-253.
PMID: 37757996
Purpose: Retinal drusen have been described in people with IgA nephropathy. We examined the frequency of drusen in IgA nephropathy and compared their location and composition with those for drusen...
8.
Ma J, Greferath U, Wong J, Fothergill L, Jobling A, Vessey K, et al.
Neurobiol Aging
. 2023 May;
128:1-16.
PMID: 37130462
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss and dysfunction in the retinal pigment epithelium (RPE) with age is known to contribute to disease development. The...
9.
Wong J, Ma J, Jobling A, Brandli A, Greferath U, Fletcher E, et al.
Front Neurosci
. 2022 Nov;
16:1009599.
PMID: 36408381
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit...
10.
Vessey K, Jobling A, Tran M, Wang A, Greferath U, Fletcher E
Autophagy
. 2022 Feb;
18(10):2368-2384.
PMID: 35196199
Age-related macular degeneration (AMD) is a leading cause of vision loss with recent evidence indicating an important role for macroautophagy/autophagy in disease progression. In this study we investigate the efficacy...