Andrew I Jobling
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Explore the profile of Andrew I Jobling including associated specialties, affiliations and a list of published articles.
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51
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1086
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Recent Articles
1.
Jobling A, Greferath U, Dixon M, Quiriconi P, Eyar B, van Koeverden A, et al.
Prog Retin Eye Res
. 2025 Feb;
106:101349.
PMID: 40020909
The high metabolic demand of retinal neurons requires a precisely regulated vascular system that can deliver rapid changes in blood flow in response to neural need. In the retina, this...
2.
Vessey K, Jobling A, Greferath U, Fletcher E
Curr Opin Pharmacol
. 2024 May;
76:102463.
PMID: 38788268
Age-related macular degeneration (AMD) is a major cause of irreversible vision loss in the elderly. Although new therapies have recently emerged, there are currently no ways of preventing the development...
3.
Ma J, Greferath U, Wong J, Fothergill L, Jobling A, Vessey K, et al.
Neurobiol Aging
. 2023 May;
128:1-16.
PMID: 37130462
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss and dysfunction in the retinal pigment epithelium (RPE) with age is known to contribute to disease development. The...
4.
Wong J, Ma J, Jobling A, Brandli A, Greferath U, Fletcher E, et al.
Front Neurosci
. 2022 Nov;
16:1009599.
PMID: 36408381
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the older population. Classical hallmarks of early and intermediate AMD are accumulation of drusen, a waste deposit...
5.
Fletcher E, Dixon M, Mills S, Jobling A
Clin Exp Ophthalmol
. 2022 Nov;
51(1):81-91.
PMID: 36349522
Diabetic retinopathy is the most feared complication for those with diabetes. Although visible vascular pathology traditionally defines the management of this condition, it is now recognised that a range of...
6.
Vessey K, Jobling A, Tran M, Wang A, Greferath U, Fletcher E
Autophagy
. 2022 Feb;
18(10):2368-2384.
PMID: 35196199
Age-related macular degeneration (AMD) is a leading cause of vision loss with recent evidence indicating an important role for macroautophagy/autophagy in disease progression. In this study we investigate the efficacy...
7.
Mills S, Jobling A, Dixon M, Bui B, Vessey K, Phipps J, et al.
Proc Natl Acad Sci U S A
. 2021 Dec;
118(51).
PMID: 34903661
Local blood flow control within the central nervous system (CNS) is critical to proper function and is dependent on coordination between neurons, glia, and blood vessels. Macroglia, such as astrocytes...
8.
Nencini S, Morgan M, Thai J, Jobling A, Mazzone S, Ivanusic J
Front Physiol
. 2021 Aug;
12:644929.
PMID: 34335288
Piezo2 is a mechanically gated ion-channel that has a well-defined role in innocuous mechanical sensitivity, but recently has also been suggested to play a role in mechanically induced pain. Here...
9.
Dixon M, Greferath U, Fletcher E, Jobling A
Front Cell Neurosci
. 2021 May;
15:659843.
PMID: 33967697
Microglia, the resident immune cells of the central nervous system (CNS), were once considered quiescent cells that sat in readiness for reacting to disease and injury. Over the last decade,...
10.
Cohn A, Wu Z, Jobling A, Fletcher E, Guymer R
J Clin Med
. 2021 Feb;
10(3).
PMID: 33525639
The presence of drusen is an important hallmark of age-related macular degeneration (AMD). Laser-induced regression of drusen, first observed over four decades ago, has led to much interest in the...