Uri Hershberg
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Explore the profile of Uri Hershberg including associated specialties, affiliations and a list of published articles.
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48
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1770
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Recent Articles
21.
Toby I, Levin M, Salinas E, Christley S, Bhattacharya S, Breden F, et al.
BMC Bioinformatics
. 2016 Oct;
17(Suppl 13):333.
PMID: 27766961
Background: The genes that produce antibodies and the immune receptors expressed on lymphocytes are not germline encoded; rather, they are somatically generated in each developing lymphocyte by a process called...
22.
Rosenfeld A, Meng W, Luning Prak E, Hershberg U
Bioinformatics
. 2016 Sep;
33(2):292-293.
PMID: 27616708
Availability And Implementation: ImmuneDB is freely available at http://immunedb.comA demo of the ImmuneDB web interface is available at: http://immunedb.com/demo CONTACT: Uh25@drexel.eduSupplementary information: Supplementary data are available at Bioinformatics online.
23.
C Antell G, Dampier W, Aiamkitsumrit B, Nonnemacher M, Jacobson J, Pirrone V, et al.
Retrovirology
. 2016 May;
13(1):32.
PMID: 27143130
Background: HIV-1 entry is a receptor-mediated process directed by the interaction of the viral envelope with the host cell CD4 molecule and one of two co-receptors, CCR5 or CXCR4. The...
24.
Liu X, Berry C, Ruthel G, Madara J, MacGillivray K, Gray C, et al.
J Biol Chem
. 2016 Jan;
291(16):8440-52.
PMID: 26826124
T cell activation following antigen binding to the T cell receptor (TCR) involves the mobilization of intracellular Ca(2+) to activate the key transcription factors nuclear factor of activated T lymphocytes...
25.
Zhang B, Meng W, Luning Prak E, Hershberg U
J Immunol Methods
. 2015 Nov;
427:105-16.
PMID: 26529062
Immune repertoires are collections of lymphocytes that express diverse antigen receptor gene rearrangements consisting of Variable (V), (Diversity (D) in the case of heavy chains) and Joining (J) gene segments....
26.
Winter M, Liu M, Monteleone D, Melunis J, Hershberg U, Goderie S, et al.
Stem Cell Reports
. 2015 Sep;
5(4):609-20.
PMID: 26344906
Time-lapse microscopy can capture patterns of development through multiple divisions for an entire clone of proliferating cells. Images are taken every few minutes over many days, generating data too vast...
27.
Hershberg U, Luning Prak E
Philos Trans R Soc Lond B Biol Sci
. 2015 Jul;
370(1676).
PMID: 26194753
Clones are the fundamental building blocks of immune repertoires. The number of different clones relates to the diversity of the repertoire, whereas their size and sequence diversity are linked to...
28.
Reichenberger E, Rosen G, Hershberg U, Hershberg R
Genome Biol Evol
. 2015 Apr;
7(5):1380-9.
PMID: 25861819
The causes of the great variation in nucleotide composition of prokaryotic genomes have long been disputed. Here, we use extensive metagenomic and whole-genome data to demonstrate that both phylogeny and...
29.
Saini J, Hershberg U
Mol Immunol
. 2015 Feb;
65(1):157-67.
PMID: 25660968
The exceptional ability of B cells to diversify through somatic mutation and improve affinity of the repertoire toward the antigens is the cornerstone of adaptive immunity. Somatic mutation is not...
30.
Hamza N, Hershberg U, Kallenberg C, Vissink A, Spijkervet F, Bootsma H, et al.
J Immunol
. 2014 Dec;
194(2):514-21.
PMID: 25488989
In this study, we sought to understand the selective pressures shaping the Ig-producing cell repertoire in the parotid glands of primary Sjögren's syndrome (pSS) patients before and after rituximab treatment...