Umberto Di Vicino
Overview
Explore the profile of Umberto Di Vicino including associated specialties, affiliations and a list of published articles.
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20
Citations
558
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Recent Articles
1.
Nakagawa S, Carnevali D, Tan X, Alvarez M, Parfitt D, Di Vicino U, et al.
Stem Cell Reports
. 2024 May;
19(5):689-709.
PMID: 38701778
Embryo size, specification, and homeostasis are regulated by a complex gene regulatory and signaling network. Here we used gene expression signatures of Wnt-activated mouse embryonic stem cell (mESC) clones to...
2.
Pesaresi M, Bonilla-Pons S, Sebastian-Perez R, Di Vicino U, Alcoverro-Bertran M, Michael R, et al.
Mol Ther
. 2020 Dec;
29(2):804-821.
PMID: 33264643
Cell therapy approaches hold great potential for treating retinopathies, which are currently incurable. This study addresses the problem of inadequate migration and integration of transplanted cells into the host retina....
3.
Zhang M, Lai Y, Krupalnik V, Guo P, Guo X, Zhou J, et al.
Sci Adv
. 2020 Aug;
6(29):eaba1593.
PMID: 32832621
Mouse embryonic stem cells cultured with MEK (mitogen-activated protein kinase kinase) and GSK3 (glycogen synthase kinase 3) inhibitors (2i) more closely resemble the inner cell mass of preimplantation blastocysts than...
4.
Ritschka B, Knauer-Meyer T, Sampaio Goncalves D, Mas A, Plassat J, Durik M, et al.
Genes Dev
. 2020 Mar;
34(7-8):489-494.
PMID: 32139422
Young mammals possess a limited regenerative capacity in some tissues, which is lost upon maturation. We investigated whether cellular senescence might play a role in such loss during liver regeneration....
5.
Frade J, Nakagawa S, Cortes P, Di Vicino U, Romo N, Lluis F, et al.
Sci Adv
. 2019 Oct;
5(10):eaax4199.
PMID: 31663024
Cells with high ploidy content are common in mammalian extraembryonic and adult tissues. Cell-to-cell fusion generates polyploid cells during mammalian development and tissue regeneration. However, whether increased ploidy can be...
6.
Theka I, Sottile F, Cammisa M, Bonnin S, Sanchez-Delgado M, Di Vicino U, et al.
Sci Rep
. 2019 Feb;
9(1):948.
PMID: 30700782
Mouse embryonic stem cells (mESCs) are pluripotent and can differentiate into cells belonging to the three germ layers of the embryo. However, mESC pluripotency and genome stability can be compromised...
7.
Pesaresi M, Bonilla-Pons S, Simonte G, Sanges D, Di Vicino U, Cosma M
EBioMedicine
. 2018 Mar;
30:38-51.
PMID: 29525572
Müller glial cells (MGCs) represent the most plastic cell type found in the retina. Following injury, zebrafish and avian MGCs can efficiently re-enter the cell cycle, proliferate and generate new...
8.
Altarche-Xifro W, Di Vicino U, Munoz-Martin M, Bortolozzi A, Bove J, Vila M, et al.
EBioMedicine
. 2016 Jul;
8:83-95.
PMID: 27428421
Parkinson's disease is a common neurodegenerative disorder, which is due to the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and for which no definitive cure is...
9.
Sanges D, Simonte G, Di Vicino U, Romo N, Pinilla I, Nicolas M, et al.
J Clin Invest
. 2016 Jul;
126(8):3104-16.
PMID: 27427986
Vision impairments and blindness caused by retinitis pigmentosa result from severe neurodegeneration that leads to a loss of photoreceptors, the specialized light-sensitive neurons that enable vision. Although the mammalian nervous...
10.
Marucci L, Pedone E, Di Vicino U, Sanuy-Escribano B, Isalan M, Cosma M
Cell Rep
. 2014 Sep;
8(6):1686-1696.
PMID: 25199832
The Wnt/β-catenin pathway and Nanog are key regulators of embryonic stem cell (ESC) pluripotency and the reprogramming of somatic cells. Here, we demonstrate that the repression of Dkk1 by Nanog,...