Ulf Lindahl
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Explore the profile of Ulf Lindahl including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Seidel P, Rolander B, Eriksson A, Lindahl U, Wallerstedt S, Hagg S, et al.
Eur J Clin Pharmacol
. 2023 Apr;
79(6):767-774.
PMID: 37059830
Purpose: This study aimed to explore physicians' use of drug information in professional work, with special focus on those working in primary care, and also in relation to personal characteristics...
2.
Zhang T, Yu M, Li H, Maccarana M, Zhang W, Shi D, et al.
Carbohydr Polym
. 2023 Mar;
299:120191.
PMID: 36876765
Glucuronyl 5-epimerase (Hsepi) converts D-glucuronic acid (GlcA) into L-iduronic acid (IdoA) units, through a mechanism involving reversible abstraction of a proton at C5 of hexuronic acid residues. Incubations of a...
3.
Zhang X, OCallaghan P, Li H, Tan Y, Zhang G, Barash U, et al.
Acta Neuropathol Commun
. 2021 May;
9(1):84.
PMID: 33971986
Defective amyloid-β (Aβ) clearance from the brain is a major contributing factor to the pathophysiology of Alzheimer's disease (AD). Aβ clearance is mediated by macrophages, enzymatic degradation, perivascular drainage along...
4.
5.
Lindahl U, Li J
Adv Exp Med Biol
. 2020 Apr;
1221:61-69.
PMID: 32274706
Heparanase was discovered during a study of the heparin proteoglycan (serglycin) in mast cells. Newly synthesized polysaccharide chains, kDa 60-100 x 10, were rapidly degraded to fragments similar in size...
6.
Kjellen L, Lindahl U
Curr Opin Struct Biol
. 2018 Feb;
50:101-108.
PMID: 29455055
Glycosaminoglycans (GAGs) interact with a variety of proteins with important functions in development and homeostasis. Most of these proteins bind to heparin in vitro, a highly sulfated GAG species, although...
7.
A potential role for chondroitin sulfate/dermatan sulfate in arm regeneration in Amphiura filiformis
Ramachandra R, Namburi R, Dupont S, Ortega-Martinez O, van Kuppevelt T, Lindahl U, et al.
Glycobiology
. 2017 Jan;
27(5):438-449.
PMID: 28130266
Glycosaminoglycans (GAGs), such as chondroitin sulfate (CS) and dermatan sulfate (DS) from various vertebrate and invertebrate sources are known to be involved in diverse cellular mechanisms during repair and regenerative...
8.
Fang J, Song T, Lindahl U, Li J
Sci Rep
. 2016 Aug;
6:31242.
PMID: 27511124
Biosynthesis of heparan sulfate (HS) involves conversion of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) units catalyzed by glucuronyl C5-epimerase (Hsepi). IdoA units are the favored substrate for 2-O-sulfotransferase (2OST)....
9.
OCallaghan P, Li J, Lannfelt L, Lindahl U, Zhang X
J Biol Chem
. 2015 Apr;
290(24):14904-14.
PMID: 25869127
Microglia rapidly mount an inflammatory response to pathogens in the central nervous system (CNS). Heparan sulfate proteoglycans (HSPGs) have been attributed various roles in inflammation. To elucidate the relevance of...
10.
OCallaghan P, Noborn F, Sehlin D, Li J, Lannfelt L, Lindahl U, et al.
Amyloid
. 2014 Feb;
21(2):76-87.
PMID: 24491019
The increased risk of Alzheimer's disease (AD) associated with specific apolipoprotein E (ApoE) isoforms appears to relate to altered amyloid-β (Aβ) homeostasis. Clearance of Aβ from the brain is reduced...