Ugo Chianese
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Explore the profile of Ugo Chianese including associated specialties, affiliations and a list of published articles.
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20
Citations
129
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Recent Articles
1.
Benedetti R, Chianese U, Papulino C, Scisciola L, Cortese M, Formisano P, et al.
Eur J Heart Fail
. 2025 Jan;
PMID: 39809551
Aims: Hyperglycaemic conditions increase cardiac stress, a common phenomenon associated with inflammation, aging, and metabolic imbalance. Sodium-glucose cotransporter 2 inhibitors, a class of anti-diabetic drugs, showed to improve cardiovascular functions...
2.
Papulino C, Chianese U, Ali A, Favale G, Tuccillo C, Ciardiello F, et al.
J Transl Med
. 2024 Jul;
22(1):676.
PMID: 39044184
Background: Breast cancer manifests as a heterogeneous pathology marked by complex metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost the metabolism, modifying fatty acid synthesis and glucose...
3.
Carullo G, Rossi S, Giudice V, Pezzotta A, Chianese U, Scala P, et al.
ACS Pharmacol Transl Sci
. 2024 Jul;
7(7):2125-2142.
PMID: 39022363
Blood cancers encompass a group of diseases affecting the blood, bone marrow, or lymphatic system, representing the fourth most commonly diagnosed cancer worldwide. Leukemias are characterized by the dysregulated proliferation...
4.
Sobinoff A, Di Maro S, Low R, Benedetti R, Tomassi S, DAniello A, et al.
Cell Chem Biol
. 2023 Dec;
30(12):1652-1665.e6.
PMID: 38065101
The TRF2 shelterin component is an essential regulator of telomere homeostasis and genomic stability. Mutations in the TRF2 domain physically impair t-loop formation and prevent the recruitment of several factors...
5.
Scisciola L, Chianese U, Caponigro V, Basilicata M, Salviati E, Altucci L, et al.
J Transl Med
. 2023 Sep;
21(1):662.
PMID: 37742032
Background: Sodium-glucose cotransporter 2 (SGLT2) inhibitors constitute the gold standard treatment for type 2 diabetes mellitus (T2DM). Among them, empagliflozin (EMPA) has shown beneficial effects against heart failure. Because cardiovascular...
6.
Varghese B, Chianese U, Capasso L, Sian V, Bontempo P, Conte M, et al.
J Transl Med
. 2023 Sep;
21(1):627.
PMID: 37715252
Background: Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved enzymes that play a fundamental role in energy metabolism regulation. SIRT1,...
7.
Chianese U, Papulino C, Megchelenbrink W, Tambaro F, Ciardiello F, Benedetti R, et al.
Semin Cancer Biol
. 2023 Apr;
92:84-101.
PMID: 37003397
Acute myeloid leukemia (AML) is a heterogeneous disease with a genetic, epigenetic, and transcriptional etiology mainly presenting somatic and germline abnormalities. AML incidence rises with age but can also occur...
8.
Martins-Lima C, Chianese U, Benedetti R, Altucci L, Jeronimo C, Correia M
Front Mol Biosci
. 2023 Jan;
9:1070383.
PMID: 36699696
Bladder cancer (BlCa) is a highly immunogenic cancer. Bacillus Calmette-Guérin (BCG) is the standard treatment for non-muscle invasive bladder cancer (NMIBC) patients and, recently, second-line immunotherapies have arisen to treat...
9.
Chianese U, Papulino C, Ali A, Ciardiello F, Cappabianca S, Altucci L, et al.
J Transl Med
. 2023 Jan;
21(1):32.
PMID: 36650542
Background: Pancreatic ductal adenocarcinoma (PDAC) and prostate cancer (PCa) are among the most prevalent malignant tumors worldwide. There is now a comprehensive understanding of metabolic reprogramming as a hallmark of...
10.
Montella M, Ciani G, Granata V, Fusco R, Grassi F, Ronchi A, et al.
J Pers Med
. 2022 Nov;
12(11).
PMID: 36422072
Purpose: To assess the qualitative relationship between liquid biopsy and conventional tissue biopsy. As a secondary target, we evaluated the relationship between the liquid biopsy results and the T stage,...