Rosaria Benedetti
Overview
Explore the profile of Rosaria Benedetti including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
915
Followers
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Recent Articles
1.
Fontana A, Bergantini L, Carullo G, Scalvini L, DAlessandro M, Papulino C, et al.
ACS Pharmacol Transl Sci
. 2025 Feb;
8(2):380-393.
PMID: 39974640
Idiopathic pulmonary fibrosis (IPF) is a rare interstitial lung disease typified by a progressive fibrosing phenotype. IPF has been associated with aberrant HDAC activity, particularly HDAC6. Combining synthetic and modeling...
2.
Benedetti R, Chianese U, Papulino C, Scisciola L, Cortese M, Formisano P, et al.
Eur J Heart Fail
. 2025 Jan;
PMID: 39809551
Aims: Hyperglycaemic conditions increase cardiac stress, a common phenomenon associated with inflammation, aging, and metabolic imbalance. Sodium-glucose cotransporter 2 inhibitors, a class of anti-diabetic drugs, showed to improve cardiovascular functions...
3.
Benedetti R, Altucci L
Nat Cancer
. 2024 Oct;
5(11):1602-1604.
PMID: 39455848
No abstract available.
4.
Trotta A, Mazzarella V, Roggia M, DAniello A, Bene A, Vetrei C, et al.
Eur J Med Chem
. 2024 Sep;
279:116911.
PMID: 39348763
Macrocyclization presents a valuable strategy for enhancing the pharmacokinetic and pharmacodynamic profiles of short bioactive peptides. The exploration of various macrocyclic characteristics, such as crosslinking tethers, ring size, and orientation,...
5.
Trotta A, Tomassi S, Di Maiolo G, Ierano C, Vetrei C, DAlterio C, et al.
Eur J Med Chem
. 2024 Jul;
276:116669.
PMID: 39053189
The present study describes a small library of peptides derived from a potent and selective CXCR4 antagonist (3), wherein the native disulfide bond is replaced using a side-chain to tail...
6.
Papulino C, Chianese U, Ali A, Favale G, Tuccillo C, Ciardiello F, et al.
J Transl Med
. 2024 Jul;
22(1):676.
PMID: 39044184
Background: Breast cancer manifests as a heterogeneous pathology marked by complex metabolic reprogramming essential to satisfy its energy demands. Oncogenic signals boost the metabolism, modifying fatty acid synthesis and glucose...
7.
Carullo G, Rossi S, Giudice V, Pezzotta A, Chianese U, Scala P, et al.
ACS Pharmacol Transl Sci
. 2024 Jul;
7(7):2125-2142.
PMID: 39022363
Blood cancers encompass a group of diseases affecting the blood, bone marrow, or lymphatic system, representing the fourth most commonly diagnosed cancer worldwide. Leukemias are characterized by the dysregulated proliferation...
8.
Papulino C, Benedetti R, Altucci L
Int J Cancer
. 2024 Jul;
155(9):1531-1532.
PMID: 38973564
No abstract available.
9.
Barbieri M, Prattichizzo F, La Grotta R, Matacchione G, Scisciola L, Fontanella R, et al.
Ageing Res Rev
. 2024 Jul;
99:102405.
PMID: 38971321
Diabetes mellitus, a metabolic condition affecting around 537 million individuals worldwide, poses significant challenges, particularly among the elderly population. The etiopathogenesis of type 2 diabetes (T2D) depends on a combination...
10.
Favale G, Donnarumma F, Capone V, Della Torre L, Beato A, Carannante D, et al.
Cancers (Basel)
. 2024 May;
16(9).
PMID: 38730609
Hematological malignancies are among the top five most frequent forms of cancer in developed countries worldwide. Although the new therapeutic approaches have improved the quality and the life expectancy of...