Udo Oppermann
Overview
Explore the profile of Udo Oppermann including associated specialties, affiliations and a list of published articles.
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199
Citations
7373
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Recent Articles
1.
Sun J, Philpott M, Loi D, Hoffman G, Robson J, Mehta N, et al.
Commun Biol
. 2025 Jan;
8(1):67.
PMID: 39819888
Single-cell transcriptomics, which utilises barcodes and unique molecular identifiers (UMIs) for polyA+ mRNA capture, is compromised by oligonucleotide synthesis errors. To address this, we modified the oligonucleotide capture design and...
2.
Pessentheiner A, Spann N, Autran C, Oh T, Grunddal K, Coker J, et al.
JCI Insight
. 2024 Sep;
9(21).
PMID: 39325548
Macrophages contribute to the induction and resolution of inflammation and play a central role in chronic low-grade inflammation in cardiovascular diseases caused by atherosclerosis. Human milk oligosaccharides (HMOs) are complex...
3.
Van Oekelen O, Amatangelo M, Guo M, Upadhyaya B, Cribbs A, Kelly G, et al.
Cell Rep Med
. 2024 May;
5(6):101584.
PMID: 38776911
Iberdomide is a potent cereblon E3 ligase modulator (CELMoD agent) with promising efficacy and safety as a monotherapy or in combination with other therapies in patients with relapsed/refractory multiple myeloma...
4.
Chang C, Liu F, Militi S, Hester S, Nibhani R, Deng S, et al.
Nat Commun
. 2024 Apr;
15(1):3580.
PMID: 38678032
The lethality, chemoresistance and metastatic characteristics of cancers are associated with phenotypically plastic cancer stem cells (CSCs). How the non-cell autonomous signalling pathways and cell-autonomous transcriptional machinery orchestrate the stem...
5.
Xiong Y, Greschik H, Johansson C, Seifert L, Gamble V, Park K, et al.
J Med Chem
. 2024 Mar;
67(7):5837-5853.
PMID: 38533580
The methyl-lysine reader protein SPIN1 plays important roles in various human diseases. However, targeting methyl-lysine reader proteins has been challenging. Very few cellularly active SPIN1 inhibitors have been developed. We...
6.
Sun J, Philpott M, Loi D, Li S, Monteagudo-Mesas P, Hoffman G, et al.
Nat Methods
. 2024 Feb;
21(3):401-405.
PMID: 38317008
Unique molecular identifiers are random oligonucleotide sequences that remove PCR amplification biases. However, the impact that PCR associated sequencing errors have on the accuracy of generating absolute counts of RNA...
7.
Agarwal G, Moore S, Sadler R, Varghese S, Turner A, Chen L, et al.
Haematologica
. 2024 Jan;
109(6):1960-1965.
PMID: 38268439
No abstract available.
8.
Brown E, Balaguer-Lluna L, Cribbs A, Philpott M, Campo L, Browne M, et al.
Sci Rep
. 2024 Jan;
14(1):328.
PMID: 38172189
H3K27-altered Diffuse Midline Glioma (DMG) is a universally fatal paediatric brainstem tumour. The prevalent driver mutation H3K27M creates a unique epigenetic landscape that may also establish therapeutic vulnerabilities to epigenetic...
9.
Twumasi C, Moore S, Sadler R, Jeans S, Varghese S, Turner A, et al.
Eur J Haematol
. 2023 Dec;
112(4):547-553.
PMID: 38116695
Objective: To describe determinants of persisting humoral and cellular immune response to the second COVID-19 vaccination among patients with myeloma. Methods: This is a prospective, observational study utilising the RUDYstudy.org...
10.
Watson E, Baker W, Ahern D, Loi D, Cribbs A, Oppermann U
Methods Enzymol
. 2023 Oct;
690:541-574.
PMID: 37858540
Mass cytometry provides highly multiparametric data at a single cell level, coupling the specificity and sensitivity of time-of-flight mass spectrometry with the single-cell throughput of flow cytometry. It offers great...