Tyler A Dean
Overview
Explore the profile of Tyler A Dean including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
245
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0
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Recent Articles
1.
Carroll D, Miller A, Fuhr J, Elsakr J, Ricciardi V, Del Bene A, et al.
Front Endocrinol (Lausanne)
. 2024 Aug;
15:1417437.
PMID: 39114287
Introduction: Using a non-human primate (NHP) model of maternal Western-style diet (mWSD) feeding during pregnancy and lactation, we previously reported altered offspring beta:alpha cell ratio and insulin hyper-secretion Mitochondria are...
2.
Beck E, Hetrick B, Nassar L, Turnbull D, Dean T, Gannon M, et al.
bioRxiv
. 2024 Jun;
PMID: 38826380
Early-life exposure to maternal obesity or a maternal calorically dense Western-style diet (WSD) is strongly associated with a greater risk of metabolic diseases in offspring, most notably insulin resistance and...
3.
Greyslak K, Hetrick B, Bergman B, Dean T, Wesolowski S, Gannon M, et al.
Diabetes
. 2023 Sep;
72(12):1766-1780.
PMID: 37725952
Article Highlights: In lean, active adolescent offspring, a postweaning Western-style diet (pwWD) leads to shifts in body fat distribution that are associated with poorer insulin sensitivity. Fatty acid-linked oxidative metabolism...
4.
Carroll D, Elsakr J, Miller A, Fuhr J, Lindsley S, Kirigiti M, et al.
Am J Physiol Endocrinol Metab
. 2023 May;
324(6):E577-E588.
PMID: 37134140
Maternal overnutrition is associated with increased susceptibility to type 2 diabetes in the offspring. Rodent models have shown that maternal overnutrition influences islet function in offspring. To determine whether maternal...
5.
Nash M, Dobrinskikh E, Soderborg T, Janssen R, Takahashi D, Dean T, et al.
Cell Rep
. 2023 Apr;
42(4):112393.
PMID: 37058409
Maternal overnutrition increases inflammatory and metabolic disease risk in postnatal offspring. This constitutes a major public health concern due to increasing prevalence of these diseases, yet mechanisms remain unclear. Here,...
6.
Elsakr J, Zhao S, Ricciardi V, Dean T, Takahashi D, Sullivan E, et al.
Sci Rep
. 2021 Jun;
11(1):12977.
PMID: 34155315
The prevalence of maternal obesity is increasing in the United States. Offspring born to women with obesity or poor glycemic control have greater odds of becoming obese and developing metabolic...
7.
Campodonico-Burnett W, Hetrick B, Wesolowski S, Schenk S, Takahashi D, Dean T, et al.
Diabetes
. 2020 May;
69(7):1389-1400.
PMID: 32354857
Infants born to mothers with obesity have a greater risk for childhood obesity and metabolic diseases; however, the underlying biological mechanisms remain poorly understood. We used a Japanese macaque model...
8.
Elsakr J, Dunn J, Tennant K, Zhao S, Kroeten K, Pasek R, et al.
Mol Metab
. 2019 May;
25:73-82.
PMID: 31036449
Objective: In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal that a calorically-dense...
9.
Wesolowski S, Mulligan C, Janssen R, Baker 2nd P, Bergman B, DAlessandro A, et al.
Mol Metab
. 2018 Oct;
18:25-41.
PMID: 30337225
Objective: Non-alcoholic fatty liver disease (NAFLD) risk begins in utero in offspring of obese mothers. A critical unmet need in this field is to understand the pathways and biomarkers underlying...
10.
Thompson J, Gustafsson H, DeCapo M, Takahashi D, Bagley J, Dean T, et al.
Front Endocrinol (Lausanne)
. 2018 May;
9:161.
PMID: 29740395
Nutritional status influences brain health and gestational exposure to metabolic disorders (e.g. obesity and diabetes) increases the risk of neuropsychiatric disorders. The aim of the present study was to further...