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Bryan C Bergman

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Articles 88
Citations 2074
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Recent Articles
1.
Broussard J, Garfield A, Zarini S, Brozinick J, Perreault L, Newsom S, et al.
Obesity (Silver Spring) . 2024 Nov; 32(12):2334-2344. PMID: 39587896
Objective: Circulating lipids are linked with insulin resistance and increased cardiovascular disease risk. We previously reported that dihydroceramides, a specific type of sphingolipid, are elevated in insulin-resistant individuals; however, little...
2.
Bergman B, Zemski Berry K, Garfield A, Keller A, Zarini S, Bowen S, et al.
J Clin Endocrinol Metab . 2024 Nov; PMID: 39484843
Context: Adipose tissue accumulation around non-adipose tissues is associated with obesity and metabolic disease. One relatively unstudied depot is peripancreatic adipose tissue (PAT) that accumulates in obesity and insulin resistance...
3.
Zemski Berry K, Garfield A, Jambal P, Zarini S, Perreault L, Bergman B
Diabetologia . 2024 Sep; 67(12):2819-2832. PMID: 39347985
Aims/hypothesis: Intracellular ceramide accumulation in specific cellular compartments is a potential mechanism explaining muscle insulin resistance in the pathogenesis of type 2 diabetes. Muscle sarcolemmal ceramide accumulation negatively impacts insulin...
4.
Gyllenhammer L, Zaegel V, Duensing A, Lixandrao M, Dabelea D, Bergman B, et al.
JCI Insight . 2024 Sep; 9(19). PMID: 39226911
Our objective was to interrogate mesenchymal stem cell (MSC) lipid metabolism and gestational exposures beyond maternal body mass that may contribute to child obesity risk. MSCs were cultured from term...
5.
McKenna C, Stierwalt H, Zemski Berry K, Ehrlicher S, Robinson M, Zarini S, et al.
Am J Physiol Endocrinol Metab . 2024 Jun; 327(2):E183-E193. PMID: 38895980
Elevated skeletal muscle diacylglycerols (DAGs) and ceramides can impair insulin signaling, and acylcarnitines (acylCNs) reflect impaired mitochondrial fatty acid oxidation, thus, the intramuscular lipid profile is indicative of insulin resistance....
6.
Many G, Sanford J, Sagendorf T, Hou Z, Nigro P, Whytock K, et al.
Nat Metab . 2024 May; 6(5):963-979. PMID: 38693320
Subcutaneous white adipose tissue (scWAT) is a dynamic storage and secretory organ that regulates systemic homeostasis, yet the impact of endurance exercise training (ExT) and sex on its molecular landscape...
7.
Jakicic J, Kohrt W, Houmard J, Miller M, Radom-Aizik S, Rasmussen B, et al.
J Appl Physiol (1985) . 2024 Apr; 137(3):473-493. PMID: 38634503
Physical activity, including structured exercise, is associated with favorable health-related chronic disease outcomes. Although there is evidence of various molecular pathways that affect these responses, a comprehensive molecular map of...
8.
Erickson M, Dobias D, Keleher M, Dabelea D, Bergman B, Broussard J, et al.
Nutrients . 2024 Jan; 16(1). PMID: 38201882
Background: Exposure to intrauterine obesity can disrupt clock gene rhythmicity in animal models. The aim of this pilot study was to determine if maternal obesity alters rhythmic expression of core...
9.
Diaz-Vegas A, Madsen S, Cooke K, Carroll L, Khor J, Turner N, et al.
Elife . 2023 Dec; 12. PMID: 38149844
Insulin resistance (IR) is a complex metabolic disorder that underlies several human diseases, including type 2 diabetes and cardiovascular disease. Despite extensive research, the precise mechanisms underlying IR development remain...
10.