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Stephanie R Wesolowski

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Articles 58
Citations 755
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Recent Articles
1.
Tanner A, Cilvik S, Nguyen M, Dobrinskikh E, Anthony R, Wesolowski S, et al.
Int J Mol Sci . 2025 Mar; 26(5). PMID: 40076531
Postnatally, glucagon acutely lowers plasma amino acid (AA) concentrations by stimulating hepatic AA catabolism, but its fetal actions remain unclear. This study tested whether a 2 h fetal glucagon infusion...
2.
Nash M, Dobrinskikh E, Al-Juboori S, Janssen R, Fernandes J, Argabright A, et al.
Liver Int . 2025 Jan; 45(2):e16236. PMID: 39865409
Background And Aims: Maternal obesity increases the risk of the paediatric form of metabolic dysfunction-associated steatotic liver disease (MASLD), affecting up to 30% of youth, but the developmental origins remain...
3.
White A, Stremming J, Wesolowski S, Al-Juboori S, Dobrinskikh E, Limesand S, et al.
Am J Physiol Endocrinol Metab . 2024 Dec; 328(1):E116-E125. PMID: 39679943
Insulin-like growth factor-1 (IGF-1) and insulin are important fetal anabolic hormones. Complications of pregnancy, such as placental insufficiency, can lead to fetal growth restriction (FGR) with low-circulating IGF-1 and insulin...
4.
Cilvik S, Boehmer B, Wesolowski S, Brown L, Rozance P
J Physiol . 2024 Oct; 602(22):6329-6345. PMID: 39383208
Fetal glucagon concentrations are elevated in the presence of a compromised intrauterine environment, as in cases of placental insufficiency and perinatal acidaemia. Our objective was to investigate the impact of...
5.
Carroll D, Miller A, Fuhr J, Elsakr J, Ricciardi V, Del Bene A, et al.
Front Endocrinol (Lausanne) . 2024 Aug; 15:1417437. PMID: 39114287
Introduction: Using a non-human primate (NHP) model of maternal Western-style diet (mWSD) feeding during pregnancy and lactation, we previously reported altered offspring beta:alpha cell ratio and insulin hyper-secretion Mitochondria are...
6.
Moore L, Lorca R, Gumina D, Wesolowski S, Reisz J, Cioffi-Ragan D, et al.
Am J Physiol Heart Circ Physiol . 2024 Jul; 327(4):H778-H792. PMID: 39028630
High-altitude (HA) hypoxia lowers uterine artery (UtA) blood flow during pregnancy and birth weight. Adenosine monophosphate kinase (AMPK) activation has selective, uteroplacental vasodilator effects that lessen hypoxia-associated birth weight reductions....
7.
Bolte E, Dean T, Garcia B, Seferovic M, Sauter K, Hummel G, et al.
Am J Obstet Gynecol . 2024 Jun; 231(3):352.e1-352.e16. PMID: 38871238
Background: In recent years, pragmatic metformin use in pregnancy has stretched to include prediabetes mellitus, type 2 diabetes mellitus, gestational diabetes mellitus, and (most recently) preeclampsia. However, with its expanded...
8.
Beck E, Hetrick B, Nassar L, Turnbull D, Dean T, Gannon M, et al.
bioRxiv . 2024 Jun; PMID: 38826380
Early-life exposure to maternal obesity or a maternal calorically dense Western-style diet (WSD) is strongly associated with a greater risk of metabolic diseases in offspring, most notably insulin resistance and...
9.
Chang E, Stremming J, Knaub L, Wesolowski S, Rozance P, Sucharov C, et al.
J Physiol . 2024 May; 602(12):2697-2715. PMID: 38743350
Fetuses affected by intrauterine growth restriction have an increased risk of developing heart disease and failure in adulthood. Compared with controls, late gestation intrauterine growth-restricted (IUGR) fetal sheep have fewer...
10.
Brown L, Rozance P, Wang D, Eroglu E, Wilkening R, Solmonson A, et al.
JCI Insight . 2024 Apr; 9(10). PMID: 38687612
Fetal growth restriction (FGR) is accompanied by early activation of hepatic glucose production (HGP), a hallmark of type 2 diabetes (T2D). Here, we used fetal hepatic catheterization to directly measure...