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Tuomas Lonnberg

Explore the profile of Tuomas Lonnberg including associated specialties, affiliations and a list of published articles. Areas
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Articles 58
Citations 196
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Recent Articles
11.
Hande M, Maity S, Lonnberg T
J Inorg Biochem . 2021 Jun; 222:111506. PMID: 34118781
A C-nucleoside derivative of phenylpyridine or the respective palladacycle was incorporated at either 3'- or 5'-terminus of a short oligodeoxynucleotide. Hybridization properties of these modified oligonucleotides were studied in a...
12.
Saleh L, Ora M, Lonnberg T
Chembiochem . 2021 Jan; 22(10):1761-1764. PMID: 33448598
A water-soluble arylmercury complex has been synthesized, and its ability to catalyze the cleavage of the phosphodiester linkage of the RNA model compound adenylyl-3',5'-(2',3'-O-methyleneadenosine) has been assessed over a pH...
13.
Ukale D, Lonnberg T
Chembiochem . 2021 Jan; 22(10):1733-1739. PMID: 33410571
Synthetic efforts towards nucleosides, nucleotides, oligonucleotides and nucleic acids covalently mercurated at one or more of their base moieties are summarized, followed by a discussion of the proposed, realized and...
14.
Aro-Heinila A, Lonnberg T, Virta P
Chembiochem . 2020 Aug; 22(2):354-358. PMID: 32827233
A highly nucleobase-discriminating metalated nucleoside analogue, 3-fluoro-2-mercuri-6-methylaniline, was incorporated into an oligonucleotide molecular beacon. Fluorescence emission spectra were measured after the addition of four different complementary strands, in which the...
15.
Maity S, Hande M, Lonnberg T
Chembiochem . 2020 Apr; 21(16):2321-2328. PMID: 32232965
Oligonucleotides incorporating a central C-nucleoside with either a rigid or flexible benzaldoxime base moiety have been synthesized, and the hybridization properties of their metallacyclic derivatives have been studied by UV...
16.
Dengale R, Thopate S, Lonnberg T
Chempluschem . 2020 Jan; 81(9):978-984. PMID: 31968801
A C-nucleoside featuring picolinamide as the base moiety has been synthesized and incorporated in the middle of a DNA oligonucleotide. The melting temperatures of duplexes formed by this modified oligonucleotide...
17.
Uttam Ukale D, Tahtinen P, Lonnberg T
Chemistry . 2020 Jan; 26(10):2164-2168. PMID: 31913530
A C-nucleoside with 6-phenyl-1H-carbazole as the base moiety has been synthesized and incorporated in the middle of an oligonucleotide. Mercuration of this modified residue at positions 1 and 8 gave...
18.
Lonnberg T
ACS Omega . 2019 Aug; 2(8):5122-5127. PMID: 31457787
To assess the plausibility of prebiotic nucleic acid polymerization by a sequential phosphitylation-sulfurization mechanism, the rates of hydrolysis and sulfurization of bis(2',3'--methyleneadenosin-5'-yl)-H-phosphonate, a dinucleoside H-phosphonate diester, have been determined over...
19.
Aro-Heinila A, Lonnberg T, Virta P
Bioconjug Chem . 2019 Jun; 30(8):2183-2190. PMID: 31246432
A 3-fluoro-6-methylaniline nucleoside was synthesized and incorporated into an oligonucleotide, and its ability to form mercury-mediated base pairs was studied. UV melting experiments revealed increased duplex stability with thymine, guanine,...
20.
Hande M, Saher O, Lundin K, Smith C, Zain R, Lonnberg T
Molecules . 2019 Mar; 24(6). PMID: 30917503
2'--Methylribo phosphorothioate oligonucleotides incorporating cyclopalladated benzylamine conjugate groups at their 5'-termini have been prepared and their ability to hybridize with a designated target sequence was assessed by conventional UV melting...