Tristan T Beaudette
Overview
Explore the profile of Tristan T Beaudette including associated specialties, affiliations and a list of published articles.
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12
Citations
433
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Recent Articles
1.
Cui L, Cohen J, Broaders K, Beaudette T, Frechet J
Bioconjug Chem
. 2011 Apr;
22(5):949-57.
PMID: 21476603
Biotherapeutic delivery is a rapidly growing field in need of new materials that are easy to modify, are biocompatible, and provide for triggered release of their encapsulated cargo. Herein, we...
2.
Cohen J, Beaudette T, Cohen J, Broaders K, Bachelder E, Frechet J
Adv Mater
. 2010 Jun;
22(32):3593-7.
PMID: 20518040
No abstract available.
3.
Bachelder E, Beaudette T, Broaders K, Frechet J, Albrecht M, Mateczun A, et al.
Mol Pharm
. 2010 Mar;
7(3):826-35.
PMID: 20230025
Toll-like receptor (TLR) agonists induce potent innate immune responses and can be used in the development of novel vaccine adjuvants. However, access to TLRs can be challenging as exemplified by...
4.
Ainslie K, Lowe R, Beaudette T, Petty L, Bachelder E, Desai T
Small
. 2009 Sep;
5(24):2857-63.
PMID: 19787677
The development of a novel microfabricated device for oral drug delivery that overcomes many of the common barriers present in the gastrointestinal tract is reported. Specifically, the attachment of targeting...
5.
Beaudette T, Cohen J, Bachelder E, Broaders K, Cohen J, Engleman E, et al.
J Am Chem Soc
. 2009 Jul;
131(30):10360-1.
PMID: 19591467
Despite the promise of precisely targeted or otherwise functionalized polymeric particulate drug delivery vehicles, typical biocompatible particles are generally not amenable to facile and selective surface modification. Herein, we report...
6.
Beaudette T, Bachelder E, Cohen J, Obermeyer A, Broaders K, Frechet J, et al.
Mol Pharm
. 2009 May;
6(4):1160-9.
PMID: 19415922
Protein-based vaccines have been explored as a safer alternative to traditional weakened or killed whole organism based vaccination strategies and have been investigated for their ability to activate the immune...
7.
Broaders K, Cohen J, Beaudette T, Bachelder E, Frechet J
Proc Natl Acad Sci U S A
. 2009 Mar;
106(14):5497-502.
PMID: 19321415
Materials that combine facile synthesis, simple tuning of degradation rate, processability, and biocompatibility are in high demand for use in biomedical applications. We report on acetalated dextran, a biocompatible material...
8.
Cohen J, Beaudette T, Tseng W, Bachelder E, Mende I, Engleman E, et al.
Bioconjug Chem
. 2008 Dec;
20(1):111-9.
PMID: 19102625
Polymeric carriers designed to encapsulate protein antigens have great potential for improving the efficacy of vaccines and immunotherapeutics for diseases such as cancer. We recently developed a carrier system based...
9.
Bachelder E, Beaudette T, Broaders K, Paramonov S, Dashe J, Frechet J
Mol Pharm
. 2008 Aug;
5(5):876-84.
PMID: 18710254
Acid-degradable particles containing a model protein antigen, ovalbumin, were prepared from a polyurethane with acetal moieties embedded throughout the polymer, and characterized by dynamic light scattering and transmission electron microscopy....
10.
Bachelder E, Beaudette T, Broaders K, Dashe J, Frechet J
J Am Chem Soc
. 2008 Jul;
130(32):10494-5.
PMID: 18630909
Dextran, a biocompatible, water-soluble polysaccharide, was modified at its hydroxyls with acetal moieties such that it became insoluble in water but freely soluble in common organic solvents enabling its use...