Eric M Bachelder
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Explore the profile of Eric M Bachelder including associated specialties, affiliations and a list of published articles.
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96
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1699
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Recent Articles
1.
Barbery B, Lukesh N, Bachelder E, Ainslie K
Small
. 2025 Feb;
:e2409422.
PMID: 39955753
The field of immunotherapeutics is rapidly evolving with the advent of cell therapies, complex biologics, and a host of other compounds. Polymeric carriers are often used to tune the safety...
2.
Murphy C, Bachelder E, Ainslie K
Int J Pharm
. 2025 Feb;
672:125300.
PMID: 39914508
Mast cells have roles in immune regulation, allergy, and host response to pathogens. Compounds that activate mast cells (MCAs) can serve as vaccine adjuvants, potentially outperforming current FDA-approved options, especially...
3.
Stiepel R, Simpson S, Lukesh N, Middleton D, Hendy D, Ontiveros-Padilla L, et al.
ACS Nano
. 2025 Jan;
19(3):3764-3780.
PMID: 39812522
Multiple sclerosis (MS) is a severe autoimmune disorder that wreaks havoc on the central nervous system, leading to a spectrum of motor and cognitive impairments. There is no cure, and...
4.
Williamson G, Middleton D, Ainslie K, Bachelder E
Expert Opin Drug Deliv
. 2024 Dec;
22(1):1-5.
PMID: 39709953
No abstract available.
5.
Ontiveros-Padilla L, Bachelder E, Ainslie K
J Control Release
. 2024 Oct;
376:880-898.
PMID: 39427775
Influenza infections are a health public problem worldwide every year with the potential to become the next pandemic. Vaccination is the most effective strategy to prevent future influenza outbreaks, however,...
6.
Ehrenzeller S, Lukesh N, Stiepel R, Middleton D, Nuzzolo S, Tate A, et al.
RSC Pharm
. 2024 Oct;
1(4):727-741.
PMID: 39415944
Rapamycin (rapa), an immunosuppressive medication, has demonstrated considerable effectiveness in reducing organ transplant rejection and treating select autoimmune diseases. However, the standard oral administration of rapa results in poor bioavailability,...
7.
Zhang X, Shi H, Hendy D, Bachelder E, Ainslie K, Ross T
mSphere
. 2024 Jun;
9(7):e0016024.
PMID: 38920382
Importance: Influenza viruses cause severe respiratory disease, particularly in the very young and the elderly. Next-generation influenza vaccines are needed to protect against new influenza variants. This report used a...
8.
Simpson S, Middleton D, Lukesh N, Islam M, Ehrenzeller S, Bachelder E, et al.
J Pharm Sci
. 2024 Jun;
113(11):3196-3205.
PMID: 38852674
New approaches to treat autoimmune diseases are needed, and we can be inspired by mechanisms in immune tolerance to guide the design of these approaches. Efferocytosis, the process of phagocyte-mediated...
9.
Hendy D, Ma Y, Dixon T, Murphy C, Pena E, Carlock M, et al.
J Control Release
. 2024 Jun;
372:168-175.
PMID: 38844178
Influenza outbreaks are a major burden worldwide annually. While seasonal vaccines do provide protection against infection, they are limited in that they need to be updated every year to account...
10.
Roque 3rd J, Lukesh N, Hendy D, Dixon T, Islam M, Ontiveros-Padilla L, et al.
Int J Pharm
. 2024 Apr;
656:124076.
PMID: 38569976
Vaccines represent a pivotal health advancement for preventing infection. However, because carrier systems with repeated administration can invoke carrier-targeted immune responses that diminish subsequent immune responses (e.g., PEG antibodies), there...