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Trevor C Charles

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Articles 78
Citations 945
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Recent Articles
1.
Thakor A, Charles T
Trends Biotechnol . 2025 Feb; 43(3):533-539. PMID: 40015250
The Asilomar Conference on Recombinant DNA, held in 1975, established guidelines for recombinant DNA (rDNA) research and laid the foundation for biotechnology regulations. While rDNA has driven significant advancements in...
2.
Swarup S, Gupta A, Chung M, Radhakrishnan V, Davis V, Lynch M, et al.
BMC Complement Med Ther . 2025 Feb; 25(1):51. PMID: 39939954
Background: The human microbiome plays a vital role in human health, mediated by the gut-brain axis, with a large diversity of functions and physiological benefits. The dynamics and mechanisms of...
3.
Overton A, Knapp J, Lawal O, Gibson R, Fedynak A, Adebiyi A, et al.
Sci Rep . 2024 Nov; 14(1):26534. PMID: 39489759
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has shown wastewater (WW) surveillance to be an effective means of tracking the emergence of viral lineages which arrive by many...
4.
Ma M, Ardalan A, Van Dyk A, Charles T, Horsman G
FEMS Microbiol Lett . 2024 Oct; 371. PMID: 39419776
Glyphosate is the most used herbicide on Earth. After a half-century of use we know only two biodegradative pathways, each of which appears to degrade glyphosate incidentally. One pathway begins...
5.
Yang Y, Tse Y, Zhang Q, Wong K, Yang C, Yang Y, et al.
J Med Chem . 2024 Sep; 67(19):17542-17550. PMID: 39340453
Target identification is crucial for elucidating the mechanisms of bioactive molecules in drug discovery. However, traditional methods assess compounds individually, making it challenging to efficiently examine multiple compounds in parallel,...
6.
Kostic T, Schloter M, Arruda P, Berg G, Charles T, Cotter P, et al.
Microb Biotechnol . 2024 Sep; 17(9):e14550. PMID: 39236296
In recent years, microbiomes and their potential applications for human, animal or plant health, food production and environmental management came into the spotlight of major national and international policies and...
7.
Ellmen I, Overton A, Knapp J, Nash D, Ho H, Hungwe Y, et al.
Sci Rep . 2024 Aug; 14(1):20273. PMID: 39217200
Wastewater surveillance of SARS-CoV-2 has emerged as a critical tool for tracking the spread of COVID-19. In addition to estimating the relative case numbers using quantitative PCR, SARS-CoV-2 genomic RNA...
8.
Sutcliffe S, Kraemer S, Ellmen I, Knapp J, Overton A, Nash D, et al.
Microb Genom . 2024 May; 10(5). PMID: 38785221
Wastewater-based surveillance (WBS) is an important epidemiological and public health tool for tracking pathogens across the scale of a building, neighbourhood, city, or region. WBS gained widespread adoption globally during...
9.
Nash D, Ellmen I, Knapp J, Menon R, Overton A, Cheng J, et al.
Viruses . 2024 Mar; 16(3). PMID: 38543825
Tomato Brown Rugose Fruit Virus (ToBRFV) is a plant pathogen that infects important crop species and can dramatically reduce tomato crop yields. The ToBRFV has rapidly spread around the globe...
10.
Thakali O, Mercier E, Eid W, Wellman M, Brasset-Gorny J, Overton A, et al.
Sci Rep . 2024 Feb; 14(1):3728. PMID: 38355869
Wastewater surveillance of coronavirus disease 2019 (COVID-19) commonly applies reverse transcription-quantitative polymerase chain reaction (RT-qPCR) to quantify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA concentrations in wastewater over time....