Trachette L Jackson
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Explore the profile of Trachette L Jackson including associated specialties, affiliations and a list of published articles.
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40
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962
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Recent Articles
1.
Kara E, Jackson T, Jones C, Sison R, McGee Ii R
NPJ Syst Biol Appl
. 2024 Sep;
10(1):105.
PMID: 39341801
As an adoptive cellular therapy, Chimeric Antigen Receptor T cell (CAR T cell) therapy has shown remarkable success in hematological malignancies but only limited efficacy against solid tumors. Compared with...
2.
Wang Y, Bergman D, Trujillo E, Fernald A, Li L, Pearson A, et al.
Cancers (Basel)
. 2024 Sep;
16(17).
PMID: 39272799
Since the introduction of the first immune checkpoint inhibitor (ICI), immunotherapy has changed the landscape of molecular therapeutics for cancers. However, ICIs do not work equally well on all cancers...
3.
Bergman D, Wang Y, Trujillo E, Fernald A, Li L, Pearson A, et al.
Front Immunol
. 2024 Mar;
15:1358019.
PMID: 38515743
Bladder cancer is an increasingly prevalent global disease that continues to cause morbidity and mortality despite recent advances in treatment. Immune checkpoint inhibitors (ICI) and fibroblast growth factor receptor (FGFR)-targeted...
4.
Wang Y, Bergman D, Trujillo E, Pearson A, Sweis R, Jackson T
Sci Rep
. 2023 Dec;
13(1):22541.
PMID: 38110479
Immunotherapy has dramatically transformed the cancer treatment landscape largely due to the efficacy of immune checkpoint inhibitors (ICIs). Although ICIs have shown promising results for many patients, the low response...
5.
Bergman D, Jackson T
PLoS One
. 2023 Feb;
18(2):e0281672.
PMID: 36780481
Agent-based models (ABMs) are an increasingly important tool for understanding the complexities presented by phenotypic and spatial heterogeneity in biological tissue. The resolution a modeler can achieve in these regards...
6.
Jain H, Norton K, Prado B, Jackson T
Front Mol Biosci
. 2023 Jan;
9:1056461.
PMID: 36619168
Multiscale systems biology is having an increasingly powerful impact on our understanding of the interconnected molecular, cellular, and microenvironmental drivers of tumor growth and the effects of novel drugs and...
7.
Bergman D, Jackson T
STAR Protoc
. 2022 Oct;
3(4):101777.
PMID: 36313535
This protocol explains how to take an agent-based model (ABM) with molecular dynamics and set it up to solve the molecular dynamics with a global approach. It can be used...
8.
Bergman D, Sweis R, Pearson A, Nazari F, Jackson T
iScience
. 2022 May;
25(6):104387.
PMID: 35637730
Agent-based models (ABMs) are a natural platform for capturing the multiple time and spatial scales in biological processes. However, these models are computationally expensive, especially when including molecular-level effects. The...
9.
Okuneye K, Bergman D, Bloodworth J, Pearson A, Sweis R, Jackson T
Comput Syst Oncol
. 2022 Jan;
1(2).
PMID: 34984415
Bladder cancer is a common malignancy with over 80,000 estimated new cases and nearly 18,000 deaths per year in the United States alone. Therapeutic options for metastatic bladder cancer had...
10.
Storey K, Jackson T
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771476
Oncolytic viral therapies and immunotherapies are of growing clinical interest due to their selectivity for tumor cells over healthy cells and their immunostimulatory properties. These treatment modalities provide promising alternatives...