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Amy L Bauer

Explore the profile of Amy L Bauer including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 498
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Recent Articles
1.
Shamloo A, Mohammadaliha N, Heilshorn S, Bauer A
Ann Biomed Eng . 2015 Aug; 44(4):929-41. PMID: 26271521
A thorough understanding of determining factors in angiogenesis is a necessary step to control the development of new blood vessels. Extracellular matrix density is known to have a significant influence...
2.
Parsons E, Favaro B, Alonso Aguirre A, Bauer A, Blight L, Cigliano J, et al.
Conserv Biol . 2014 May; 28(5):1206-14. PMID: 24779474
The ocean provides food, economic activity, and cultural value for a large proportion of humanity. Our knowledge of marine ecosystems lags behind that of terrestrial ecosystems, limiting effective protection of...
3.
Nowak-Lovato K, Alexandrov L, Banisadr A, Bauer A, Bishop A, Usheva A, et al.
PLoS Comput Biol . 2013 Jan; 9(1):e1002881. PMID: 23341768
Physicochemical properties of DNA, such as shape, affect protein-DNA recognition. However, the properties of DNA that are most relevant for predicting the binding sites of particular transcription factors (TFs) or...
4.
Hatzikirou H, Chauviere A, Bauer A, Leier A, Lewis M, Macklin P, et al.
Wiley Interdiscip Rev Syst Biol Med . 2011 Aug; 4(1):1-14. PMID: 21853537
Cancer is arguably the ultimate complex biological system. Solid tumors are microstructured soft matter that evolves as a consequence of spatio-temporal events at the intracellular (e.g., signaling pathways, macromolecular trafficking),...
5.
Bauer A, Hlavacek W, Unkefer P, Mu F
PLoS Comput Biol . 2010 Dec; 6(11):e1001007. PMID: 21124945
An important step in understanding gene regulation is to identify the DNA binding sites recognized by each transcription factor (TF). Conventional approaches to prediction of TF binding sites involve the...
6.
Bauer A, Jackson T, Jiang Y, Rohlf T
J Theor Biol . 2010 Mar; 264(3):838-46. PMID: 20307549
Cancer invasion and metastasis depend on tumor-induced angiogenesis, the means by which cancer cells attract and maintain a blood supply. During angiogenesis, cellular processes are tightly coordinated by signaling molecules...
7.
Bauer A, Beauchemin C, Perelson A
Inf Sci (N Y) . 2010 Feb; 179(10):1379-1389. PMID: 20161146
Agent-based models have been employed to describe numerous processes in immunology. Simulations based on these types of models have been used to enhance our understanding of immunology and disease pathology....
8.
Bauer A, Jackson T, Jiang Y
PLoS Comput Biol . 2009 Jul; 5(7):e1000445. PMID: 19629173
The extracellular matrix plays a critical role in orchestrating the events necessary for wound healing, muscle repair, morphogenesis, new blood vessel growth, and cancer invasion. In this study, we investigate...
9.
Bauer A, Jackson T, Jiang Y
Biophys J . 2007 Feb; 92(9):3105-21. PMID: 17277180
This work describes the first cell-based model of tumor-induced angiogenesis. At the extracellular level, the model describes diffusion, uptake, and decay of tumor-secreted pro-angiogenic factor. At the cellular level, the...
10.
Hui A, Bauer A, Striet J, Schnell P, Czyzyk-Krzeska M
FASEB J . 2006 Mar; 20(3):466-75. PMID: 16507764
Hypoxia-inducible factors (HIFs) are ubiquitous transcription factors that mediate adaptation to hypoxia by inducing specific sets of target genes. It is well accepted that hypoxia induces accumulation and activity of...