Toyoaki Natsume
Overview
Explore the profile of Toyoaki Natsume including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
1161
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yoshizaki Y, Ouchi Y, Kurniawan D, Yumoto E, Yoneyama Y, Rizqullah F, et al.
Sci Rep
. 2024 Dec;
14(1):31904.
PMID: 39738383
CHAMP1 (chromosome alignment-maintaining phosphoprotein 1) plays a role in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR). The CHAMP1 gene is one of the genes mutated in...
2.
Hibino K, Sakai Y, Tamura S, Takagi M, Minami K, Natsume T, et al.
Nat Commun
. 2024 Aug;
15(1):7152.
PMID: 39169041
For accurate mitotic cell division, replicated chromatin must be assembled into chromosomes and faithfully segregated into daughter cells. While protein factors like condensin play key roles in this process, it...
3.
Jones R, Ruiz J, Scaramuzza S, Nath S, Liu C, Henklewska M, et al.
iScience
. 2024 Jul;
27(7):110260.
PMID: 39055910
To ensure timely duplication of the entire eukaryotic genome, thousands of replication machineries (replisomes) act on genomic DNA at any time during S phase. In the final stages of this...
4.
Scaramuzza S, Jones R, Sadurni M, Reynolds-Winczura A, Poovathumkadavil D, Farrell A, et al.
Nat Commun
. 2023 Aug;
14(1):5071.
PMID: 37604812
Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of...
5.
Koyanagi E, Kakimoto Y, Minamisawa T, Yoshifuji F, Natsume T, Higashitani A, et al.
Nat Commun
. 2022 Nov;
13(1):7221.
PMID: 36434012
The division of labour among DNA polymerase underlies the accuracy and efficiency of replication. However, the roles of replicative polymerases have not been directly established in human cells. We developed...
6.
Grange L, Reynolds J, Ullah F, Isidor B, Shearer R, Latypova X, et al.
Nat Commun
. 2022 Nov;
13(1):6664.
PMID: 36333305
Embryonic development is dictated by tight regulation of DNA replication, cell division and differentiation. Mutations in DNA repair and replication genes disrupt this equilibrium, giving rise to neurodevelopmental disease characterized...
7.
Revathidevi S, Hosomichi K, Natsume T, Nakaoka H, Fujito N, Akatsuka H, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232425
Cowden syndrome (CS) is a rare autosomal dominant disorder associated with multiple hamartomatous and neoplastic lesions in various organs. Most CS patients have been found to have germline mutations in...
8.
Das S, Kuzin V, Cameron D, Sanford S, Jha R, Nie Z, et al.
Mol Cell
. 2021 Dec;
82(1):140-158.e12.
PMID: 34890565
High-intensity transcription and replication supercoil DNA to levels that can impede or halt these processes. As a potent transcription amplifier and replication accelerator, the proto-oncogene MYC must manage this interfering...
9.
Wiegard A, Kuzin V, Cameron D, Grosser J, Ceribelli M, Mehmood R, et al.
Mol Cell
. 2021 Nov;
81(24):5007-5024.e9.
PMID: 34767771
As cells enter mitosis, chromatin compacts to facilitate chromosome segregation yet remains transcribed. Transcription supercoils DNA to levels that can impede further progression of RNA polymerase II (RNAPII) unless it...
10.
Iemura K, Natsume T, Maehara K, Kanemaki M, Tanaka K
J Cell Biol
. 2021 May;
220(7).
PMID: 33988677
Most cancer cells show chromosomal instability, a condition where chromosome missegregation occurs frequently. We found that chromosome oscillation, an iterative chromosome motion during metaphase, is attenuated in cancer cell lines....