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Toshiyuki Tsunoda

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Articles 72
Citations 668
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Recent Articles
1.
Nishi K, Yoshimoto S, Tanaka T, Kimura S, Tsunoda T, Watanabe A, et al.
Sci Rep . 2025 Mar; 15(1):8618. PMID: 40074801
In this study, the critical role of the epipharynx in managing long-term coronavirus disease 2019 (COVID-19), and in particular, how residual SARS-CoV-2 RNA affects signalling pathways in the epipharynx were...
2.
Maruta G, Maeoka H, Tsunoda T, Akiyoshi K, Takagi S, Shirasawa S, et al.
Nucleic Acids Res . 2024 Oct; 52(21):12961-12975. PMID: 39360606
Centromeres, where the kinetochore complex binds, are susceptible to damages including DNA double-stranded breaks (DSBs). Here, we report the functional significance and the temporally and spatially distinct regulation of centromeric...
3.
Kitaguchi T, Matsumoto T, Yoshida K, Hamaguchi Y, Maruta G, Maeoka H, et al.
Anticancer Res . 2024 Jul; 44(8):3557-3565. PMID: 39060056
Background/aim: In a previous study, we have demonstrated heightened Pyra-Metho-Carnil (PMC) efficacy in nude mice with intact innate immunity that lack T and B cells. This has prompted hypothesizing that...
4.
Yoshida K, Nishi K, Ishikura S, Matsumoto T, Nakabayashi K, Yazaki R, et al.
Anticancer Res . 2023 Jul; 43(8):3717-3726. PMID: 37500165
Background/aim: Pyra-Metho-Carnil (PMC) has been identified as a novel candidate compound for treating numerous malignancies; however, its mechanism of action remains unknown. In this study, we conducted RNA-sequencing (RNA-seq) analyses...
5.
Aoki M, Tsunoda T, Koga K, Nabeshima K, Hamasaki M
Anticancer Res . 2023 Jul; 43(8):3735-3745. PMID: 37500155
Background/aim: We previously found that binding between CD73 and extracellular matrix metalloproteinase (MMP) inducer (emmprin) and suppression of CD73 in both tumour cells and fibroblasts suppressed MMP-2 production when co-cultured....
6.
Ishikura S, Yoshida K, Tsunoda T, Shirasawa S
J Biol Chem . 2022 Sep; 298(11):102528. PMID: 36162510
The centromere is an essential chromosomal structure for faithful chromosome segregation during cell division. No protein-coding genes exist at the centromeres, but centromeric DNA is actively transcribed into noncoding RNA...
7.
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, Tsunoda T, et al.
In Vivo . 2022 Sep; 36(5):2357-2364. PMID: 36099101
Background/aim: Influenza A virus (IAV) infection causes an inflammatory response to the respiratory mucosa. The viral glycoprotein hemagglutinin (HA) binds to the sialylated voltage-dependent Ca channel (Cav1.2) in ciliated epithelium....
8.
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, Tanaka T, et al.
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012469
The epipharynx, located behind the nasal cavity, is responsible for upper respiratory tract immunity; however, it is also the site of frequent acute and chronic inflammation. Previous reports have suggested...
9.
Ishida Y, Tsunoda T, Hamada Y, Tsuchiya N, Koga T, Kitaguchi T, et al.
Anticancer Res . 2022 Jul; 42(8):4103-4109. PMID: 35896269
Background/aim: Recently, endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) has been conducted for diagnosing pancreatic ductal adenocarcinoma (PDAC), after which obtained samples were used in organoid cultures. However, no standardized method for...
10.
Kinugasa T, Tsunoda T, Mizoguchi E, Okada T, Sudo T, Kawahara A, et al.
Anticancer Res . 2022 Jul; 42(8):4119-4127. PMID: 35896264
Background/aim: The cumulative cancerous rate of colitis-associated cancer (CAC) has increased exponentially in patients with ulcerative colitis (UC). We have investigated the factors involved in the carcinogenic processes of CAC...