Toshiyuki Tsunoda
Overview
Explore the profile of Toshiyuki Tsunoda including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
668
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Recent Articles
11.
Yoshida K, Nishi K, Ishikura S, Nakabayashi K, Yazaki R, Ohshima T, et al.
Anticancer Res
. 2022 Jul;
42(8):3993-4001.
PMID: 35896235
Background/aim: In a screen of compounds to selectively suppress the growth of cancer spheroids, which contained mutant (mt) KRAS, NPD10621 was discovered and associated derivatives were investigated. Materials And Methods:...
12.
Terado T, Kim C, Ushio A, Minami K, Tambe Y, Kageyama S, et al.
Int J Oncol
. 2022 Jul;
61(3).
PMID: 35894141
Pyruvate dehydrogenase kinase 4 (PDK4) is an important regulator of energy metabolism. Previously, knockdown of PDK4 by specific small interfering RNAs (siRNAs) have been shown to suppress the expression of...
13.
Imai K, Yamano T, Nishi S, Nishi R, Nishi T, Tanaka H, et al.
Viruses
. 2022 May;
14(5).
PMID: 35632649
COVID-19 often causes sequelae after initial recovery, referred to collectively as long COVID. Long COVID is considered to be caused by the persistence of chronic inflammation after acute COVID-19 infection....
14.
Nishi K, Yoshimoto S, Nishi S, Tsunoda T, Ohno J, Yoshimura M, et al.
In Vivo
. 2022 Jan;
36(1):371-374.
PMID: 34972736
Background: The epipharynx, with its high expression of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) entry factors angiotensin-converting enzyme 2 (ACE2) and transmembrane protease, serine 2 (TMPRSS2), is a primary...
15.
Ishikura S, Yoshida K, Hashimoto S, Nakabayashi K, Tsunoda T, Shirasawa S
J Biol Chem
. 2021 Sep;
297(4):101213.
PMID: 34547289
The centromere is a chromosomal locus that is essential for the accurate segregation of chromosomes during cell division. Transcription of noncoding RNA (ncRNA) at the centromere plays a crucial role...
16.
Kushima H, Tsunoda T, Matsumoto T, Kinoshita Y, Izumikawa K, Shirasawa S, et al.
Microorganisms
. 2021 Aug;
9(7).
PMID: 34361872
Background/aim: is often detected in respiratory samples from patients with chronic respiratory diseases, including pulmonary fibrosis, suggesting that it can easily colonize the airways. To determine the role of colonization...
17.
Hashimoto S, Nagai M, Nishi K, Ishikura S, Nakabayashi K, Yazaki R, et al.
Anticancer Res
. 2021 Jul;
41(8):4061-4070.
PMID: 34281875
Background/aim: Among compounds from natural products selectively suppressing the growth of cancer spheroids, which have mutant (mt) KRAS, NP910 was selected and its derivatives explored. Materials And Methods: The area...
18.
Kandasamy P, Zlobec I, Nydegger D, Pujol-Gimenez J, Bhardwaj R, Shirasawa S, et al.
Mol Oncol
. 2021 May;
15(10):2782-2800.
PMID: 34003553
Oncogenic KRAS mutations develop unique metabolic dependencies on nutrients to support tumor metabolism and cell proliferation. In particular, KRAS mutant cancer cells exploit amino acids (AAs) such as glutamine and...
19.
Ishikura S, Nagai M, Tsunoda T, Nishi K, Tanaka Y, Koyanagi M, et al.
J Cell Biochem
. 2021 Feb;
122(6):626-638.
PMID: 33522619
Adipocytes play crucial roles in the control of whole-body energy homeostasis. Differentiation and functions of the adipocytes are regulated by various transcription factors. Zfat (zinc-finger protein with AT-hook) is a...
20.
Ishikura S, Nakabayashi K, Nagai M, Tsunoda T, Shirasawa S
Nucleic Acids Res
. 2020 Sep;
48(19):10848-10866.
PMID: 32997115
Centromeres are genomic regions essential for faithful chromosome segregation. Transcription of noncoding RNA (ncRNA) at centromeres is important for their formation and functions. Here, we report the molecular mechanism by...