Takehiko Sasazuki
Overview
Explore the profile of Takehiko Sasazuki including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
4709
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0
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Recent Articles
1.
Kusano S, Ueda S, Oryoji D, Toyoumi A, Hashimoto-Tane A, Kishi H, et al.
Int Immunol
. 2023 Jul;
35(9):447-458.
PMID: 37418020
Cry j 1 is a major allergen present in Japanese cedar (Cryptomeria japonica) pollens. Peptides with the core sequence of KVTVAFNQF from Cry j 1 ('pCj1') bind to HLA-DP5 and...
2.
Jin H, Kishida K, Arase N, Matsuoka S, Nakai W, Kohyama M, et al.
Sci Adv
. 2022 Mar;
8(9):eabj9867.
PMID: 35245125
Specific MHC class II alleles are strongly associated with susceptibility to various autoimmune diseases. Although the primary function of MHC class II molecules is to present peptides to helper T...
3.
Adachi Y, Sakai T, Terakura S, Shiina T, Suzuki S, Hamana H, et al.
Int J Hematol
. 2022 Jan;
115(3):371-381.
PMID: 35037229
Genomic deletion of donor-patient-mismatched HLA alleles in leukemic cells is a major cause of relapse after allogeneic hematopoietic stem cell transplantation (HSCT). Mismatched HLA is frequently lost as an individual...
4.
Hanada K, Kawada K, Nishikawa G, Toda K, Maekawa H, Nishikawa Y, et al.
Cancer Lett
. 2021 Sep;
522:129-141.
PMID: 34543685
Mutations of KRAS gene are found in various types of cancer, including colorectal cancer (CRC). Despite intense efforts, no pharmacological approaches are expected to be effective against KRAS-mutant cancers. Macropinocytosis...
5.
Ernst A, Hennel R, Krombach J, Kapfhammer H, Brix N, Zuchtriegel G, et al.
Front Oncol
. 2020 Sep;
10:1668.
PMID: 32984042
Radiotherapy is an essential part of multi-modal cancer therapy. Nevertheless, for certain cancer entities such as colorectal cancer (CRC) the indications of radiotherapy are limited due to anatomical peculiarities and...
6.
Morishima S, Shiina T, Suzuki S, Ogawa S, Sato-Otsubo A, Kashiwase K, et al.
Blood
. 2017 Dec;
131(7):808-817.
PMID: 29246901
HLA-DPB1 T-cell epitope (TCE) mismatching algorithm and rs9277534 SNP at the 3' untranslated region (3'UTR) in the HLA-DPB1 gene are key factors for transplant-related events in unrelated hematopoietic cell transplantation...
7.
Yoo B, Khan I, Koomson A, Gowda P, Sasazuki T, Shirasawa S, et al.
Autophagy
. 2017 Sep;
14(1):134-151.
PMID: 28933585
Activating mutations of RAS GTPase contribute to the progression of many cancers, including colorectal carcinoma. So far, attempts to develop treatments of mutant RAS-carrying cancers have been unsuccessful due to...
8.
Radhakrishnan H, Ilm K, Walther W, Shirasawa S, Sasazuki T, Daniel P, et al.
Cancer Lett
. 2017 Jun;
403:231-245.
PMID: 28649004
MACC1 was identified as a novel player in cancer progression and metastasis, but its role in death receptor-mediated apoptosis is still unexplored. We show that MACC1 knockdown sensitizes cancer cells...
9.
Toda K, Kawada K, Iwamoto M, Inamoto S, Sasazuki T, Shirasawa S, et al.
Neoplasia
. 2016 Oct;
18(11):654-665.
PMID: 27764698
A number of clinical trials have shown that KRAS mutations of colorectal cancer (CRC) can predict a lack of responses to anti-epidermal growth factor receptor-based therapy. Recently, there have been...
10.
Nishida N, Ohashi J, Khor S, Sugiyama M, Tsuchiura T, Sawai H, et al.
Sci Rep
. 2016 Apr;
6:24767.
PMID: 27091392
Associations of variants located in the HLA class II region with chronic hepatitis B (CHB) infection have been identified in Asian populations. Here, HLA imputation method was applied to determine...