Toshio Kaneda
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Explore the profile of Toshio Kaneda including associated specialties, affiliations and a list of published articles.
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85
Citations
545
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Recent Articles
1.
Hirasawa Y, Kasagi C, Koyama E, Myojin H, Tougan T, Horii T, et al.
J Nat Med
. 2024 Nov;
79(1):134-142.
PMID: 39540962
Four new bisindole alkaloids, cathagines A (1)-D (4) consisting of an aspidosperma and the fused tetracyclic 3-spirooxindole derived from an iboga type skeleton were isolated from the whole plant of...
2.
Nakajima Y, Nishino H, Takahashi K, Nugroho A, Hirasawa Y, Kaneda T, et al.
J Nat Med
. 2024 Sep;
79(1):36-44.
PMID: 39283364
Previously, we reported that azamollugin, an aza-derivative of mollugin, exhibited potent inhibitory activity on NO production in LPS-stimulated RAW 264.7 cells. Further investigations in this study revealed that azamollugin not...
3.
Nakajima Y, Tsuboi N, Katori K, Waili M, Nugroho A, Takahashi K, et al.
J Nat Med
. 2024 Apr;
78(3):568-575.
PMID: 38564154
Oxomollugin is a degraded product of mollugin and was found to be an active compound that inhibits LPS-induced NF-κB activation. In this study, we investigated the inhibitory activity of oxomollugin,...
4.
Hirasawa Y, Kase A, Okamoto A, Suzuki K, Hiroki M, Kaneda T, et al.
J Nat Med
. 2024 Feb;
78(2):382-392.
PMID: 38347371
A new dimeric indole alkaloid, vincazalidine A consisting of an aspidosperma type and a modified iboga type with 1-azatricyclo ring system consisting of one azepane and two piperidine rings coupled...
5.
Nugroho A, Komuro T, Kawaguchi T, Shindo Y, Wong C, Hirasawa Y, et al.
J Nat Med
. 2023 Sep;
78(1):68-77.
PMID: 37690111
Ceramicines are a series of limonoids which were isolated from the barks of Malaysian Chisocheton ceramicus (Meliaceae), and were known to show various biological activity. Six new limonoids, ceramicines U-Z...
6.
Hiroki M, Abulikemu A, Totsuka C, Hirasawa Y, Kaneda T, Morita H
J Nat Med
. 2023 Sep;
78(1):216-225.
PMID: 37668823
A dimeric indole alkaloid, isovincathicine consisting of an aspidosperma type and modified iboga with C-7-C-20 connection type skeletons was first isolated from Catharanthus roseus, and the structure including stereochemistry was...
7.
Nugroho A, Wong C, Hirasawa Y, Kaneda T, Tougan T, Horii T, et al.
J Nat Med
. 2023 May;
77(3):596-603.
PMID: 37162697
Ceramicines are a series of limonoids that were isolated from the bark of Malaysian Chisocheton ceramicus (Meliaceae) and were known to show various biological activity. Four new limonoids, ceramicines Q-T...
8.
Kaneda T, Ifadotunnikmah F, Nugroho A, Koshikawa S, Tadahiro S, Hirasawa Y, et al.
J Nat Prod
. 2022 Aug;
85(9):2192-2198.
PMID: 35983865
Previously, we isolated 2,3,15-calofolic acids (CAs) from bark, which showed vasorelaxant activity on phenylephrine (PE)-precontracted rat aortic rings. Although the effect was suggested to be induced via an extracellular Ca-independent...
9.
Inoue T, Fujii K, Kaneda T, Kitayama H
Vasc Endovascular Surg
. 2022 Aug;
56(8):817-819.
PMID: 35961606
Reports documenting the mid-term patency of spiral saphenous vein grafts for superior vena cava syndrome in patients with advanced thoracic malignancy are, so far, scarce. The present report describes a...
10.
Ogasawara A, Noguchi R, Shigi T, Nugroho A, Hirasawa Y, Kaneda T, et al.
J Nat Med
. 2022 Mar;
76(3):645-653.
PMID: 35316467
Bioactivity-guided separation of the methanol extract of Calophyllum scriblitifolium bark led to the isolation of five new pyranocoumarins, caloforines A-E (1-5) and two new coumarins, caloforines F and G (6...