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Tong Dai

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Articles 38
Citations 1845
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Recent Articles
1.
Wu C, Bi C, Kim G, Yang Z, Li S, Dai T, et al.
Sci Rep . 2025 Jan; 15(1):1569. PMID: 39794457
Tofacitinib (Tof), a commercially available pan-Janus kinases inhibitor, is approved for the treatment of moderate to severe ulcerative colitis. However, its clinical application is limited due to dose-dependent systemic side...
2.
Kong W, Gu G, Dai T, Chen B, Wang Y, Zeng Z, et al.
Nat Commun . 2024 Nov; 15(1):9470. PMID: 39488532
Variations of individual lifespans within genetically identical populations in homogenous environments are remarkable, with the cause largely unknown. Here, we show the expression dynamic of the Caenorhabditis elegans fatty acid...
3.
Li N, Hao S, Cao X, Lin Y, Li Y, Dai T, et al.
Quant Imaging Med Surg . 2024 Oct; 14(10):7576-7586. PMID: 39429582
Background: Glioblastoma (GBM) exhibits diffuse and invasive growth patterns, with a 5-year overall survival (OS) rate of 5-10%. In addition, approximately 40 percent of GBMs are localized in the frontal...
4.
Wang J, Zhang Z, Dai T, Zhang Z, Zhang Q, Yao J, et al.
Food Funct . 2024 Sep; 15(19):9632-9661. PMID: 39239698
Metabolic syndrome (MetS) is a disease condition incorporating the abnormal accumulation of various metabolic components, including overweight or abdominal obesity, insulin resistance and abnormal glucose tolerance, hypertension, atherosclerosis, or dyslipidemia....
5.
Cheng W, Fan Y, Dai T, Liang J, Zhu C, Shao R, et al.
World Neurosurg . 2024 Jul; 190():284-288. PMID: 38964458
Objective: We aimed to preliminarily explore the efficacy and safety of unilateral biportal endoscopy for the treatment of epidural cement leaks. We report a patient who underwent epidural cement leakage...
6.
Zhang X, He N, Zhang L, Dai T, Sun Z, Shi Y, et al.
Drug Deliv . 2024 Apr; 31(1):2342844. PMID: 38659328
High intensity focused ultrasound (HIFU) has demonstrated its safety, efficacy and noninvasiveness in the ablation of solid tumor. However, its further application is limited by its inherent deficiencies, such as...
7.
Liao Q, Shu X, Sun W, Mandapaka H, Xie F, Zhang Z, et al.
Small . 2023 Dec; 20(20):e2308383. PMID: 38073323
Acidic residues (Asp and Glu) have a high prevalence on protein surfaces, but cross-linking reactions targeting these residues are limited. Existing methods either require high-concentration coupling reagents or have low...
8.
Dai T, Zhang L, Ran Y, Zhang M, Yang B, Lu H, et al.
Nat Struct Mol Biol . 2023 May; 30(6):785-799. PMID: 37188808
Mitochondrial antiviral signaling protein (MAVS) is an adapter that recruits and activates IRF3. However, the mechanisms underpinning the interplay between MAVS and IRF3 are largely unknown. Here we show that...
9.
Wang S, Chu F, Xia R, Guan J, Zhou L, Fang X, et al.
Cell Rep . 2022 Nov; 41(8):111661. PMID: 36417850
Innate immunity is critical for the early detection and elimination of viral invasion. Extracellular signals are crucial for host resistance; however, how extracellular factors prepare the innate immunity for rapid...
10.
Evans R, Lee K, Wallace P, Reid M, Muhitch J, Dozier A, et al.
Front Oncol . 2022 Aug; 12:958043. PMID: 35992783
Background: CIMAvax-EGF is an epidermal growth factor (EGF)-depleting immunotherapy which has shown survival benefit as a switch maintenance treatment after platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC). The...