Tomoka Morita
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Explore the profile of Tomoka Morita including associated specialties, affiliations and a list of published articles.
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16
Citations
158
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Recent Articles
1.
Itabashi T, Hosoba K, Morita T, Kimura S, Yamaoka K, Hirosawa M, et al.
Life Sci Alliance
. 2025 Feb;
8(4).
PMID: 39900437
The plasma membrane covering the primary cilium has a diverse accumulation of receptors and channels. To ensure the sensor function of the cilia, the ciliary membrane has higher cholesterol content...
2.
Kimura S, Morita T, Hosoba K, Itoh H, Yamamoto T, Miyamoto T
Front Mol Biosci
. 2023 Apr;
10:1160415.
PMID: 37006607
Primary cilium is a non-motile, antenna-like structure that develops in the quiescent G phase-cell surface. It is composed of an array of axonemal microtubules polymerized from the centrosome/basal body. The...
3.
Hosoba K, Morita T, Zhang Y, Kishi H, Yamamoto T, Miyamoto T
Methods Cell Biol
. 2023 Mar;
175:85-95.
PMID: 36967147
Primary cilia are antenna-like structures developed on the cell surface of mammalian cells during the quiescent G phase. Primary cilia in mammalian cells receive extracellular signals for early development and...
4.
Li N, Zhang Y, Morita T, Kishi H, Kobayashi S
J Pharmacol Sci
. 2022 Jun;
149(4):189-197.
PMID: 35717072
We previously discovered that the SPC/Fyn/Rho-kinase (ROK) pathway mediates the Ca-sensitization of coronary arterial smooth muscle (CASM) contraction leading to vasospasm, a major cause of sudden death. Lately, we have...
5.
Kato M, Yamaguchi M, Morita T, Watanabe N, Ota S, Yamamoto E
J Chromatogr A
. 2022 Jan;
1664:462802.
PMID: 35030531
Nanoparticles are widely used in the medical field for diagnosis and therapy. In particular, the use of nanoparticles containing vaccines has spread rapidly; hence, ensuring nanoparticle safety and minimizing their...
6.
Lu Q, Kishi H, Zhang Y, Morita T, Kobayashi S
J Cardiovasc Pharmacol
. 2022 Jan;
79(4):456-466.
PMID: 34983908
Cardiovascular diseases are the leading cause of mortality and disability worldwide. We have previously found that sphingosylphosphorylcholine (SPC) is the key molecule leading to vasospasm. We have also identified the...
7.
Zhang Y, Kishi H, Morita T, Kobayashi S
FASEB J
. 2021 Nov;
35(12):e22012.
PMID: 34724245
Rho-kinase (ROK)-mediated migration of vascular smooth muscle cells plays a crucial role in cardiovascular diseases. Previously we demonstrated Fyn tyrosine kinase as an upstream molecule of ROK to mediate actin...
8.
Usui T, Sakatsume T, Nijima R, Otani K, Kazama K, Morita T, et al.
Clin Sci (Lond)
. 2014 May;
127(8):539-48.
PMID: 24814693
Death-associated protein kinase 3 (DAPK3) also known as zipper-interacting kinase is a serine/threonine kinase that mainly regulates cell death and smooth muscle contraction. We have previously found that protein expression...
9.
Morita T, Okada M, Yamawaki H
J Vet Med Sci
. 2014 Apr;
76(7):963-9.
PMID: 24694942
Organ culture of blood vessel is a better technique to investigate the long-term effects of drugs. However, some functional changes may occur from freshly isolated vessel (Fresh). Mammalian/mechanistic target of...
10.
Usui T, Morita T, Okada M, Yamawaki H
Hypertension
. 2013 Oct;
63(2):397-403.
PMID: 24166750
Histone deacetylases (HDACs) are transcriptional coregulators. Recently, we demonstrated that HDAC4, one of class IIa family members, promotes reactive oxygen species-dependent vascular smooth muscle inflammation and mediates development of hypertension...