Hiroko Kishi
Overview
Explore the profile of Hiroko Kishi including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
311
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Recent Articles
1.
Itabashi T, Hosoba K, Morita T, Kimura S, Yamaoka K, Hirosawa M, et al.
Life Sci Alliance
. 2025 Feb;
8(4).
PMID: 39900437
The plasma membrane covering the primary cilium has a diverse accumulation of receptors and channels. To ensure the sensor function of the cilia, the ciliary membrane has higher cholesterol content...
2.
Matsuzaki K, Sugimoto N, Hossain S, Islam R, Sumiyoshi E, Hashimoto M, et al.
Food Funct
. 2024 May;
15(10):5579-5595.
PMID: 38713055
Attention-deficit/hyperactivity disorder (ADHD) is a developmental disorder and dopaminergic dysfunction in the prefrontal cortex (PFC) may play a role. Our previous research indicated that theobromine (TB), a methylxanthine, enhances cognitive...
3.
Zheng H, Tsunedomi R, Xu M, Zhang Y, Kishi H, Kobayashi S, et al.
Anticancer Res
. 2024 Feb;
44(2):511-520.
PMID: 38307570
Background/aim: Colorectal cancer (CRC) is the third most common cancer worldwide, and metastasis is strongly associated with poor prognosis in patients with CRC. We have previously found that the expression...
4.
Zhang Y, Zheng H, Xu M, Maeda N, Tsunedomi R, Kishi H, et al.
Int J Mol Sci
. 2023 Nov;
24(21).
PMID: 37958964
Metastasis is the leading cause of death in breast cancer patients due to the lack of effective therapies. Elevated levels of paxillin expression have been observed in various cancer types,...
5.
Zhang Y, Kishi H, Kobayashi S
J Smooth Muscle Res
. 2023 Jul;
59:58-66.
PMID: 37438114
Vascular smooth muscle cell (VSMC) migration plays an important role in cardiovascular diseases, including atherosclerotic plaque formation and restenosis after vascular intervention. The mechanisms involved in VSMC migration are complex...
6.
Hosoba K, Morita T, Zhang Y, Kishi H, Yamamoto T, Miyamoto T
Methods Cell Biol
. 2023 Mar;
175:85-95.
PMID: 36967147
Primary cilia are antenna-like structures developed on the cell surface of mammalian cells during the quiescent G phase. Primary cilia in mammalian cells receive extracellular signals for early development and...
7.
Li N, Zhang Y, Morita T, Kishi H, Kobayashi S
J Pharmacol Sci
. 2022 Jun;
149(4):189-197.
PMID: 35717072
We previously discovered that the SPC/Fyn/Rho-kinase (ROK) pathway mediates the Ca-sensitization of coronary arterial smooth muscle (CASM) contraction leading to vasospasm, a major cause of sudden death. Lately, we have...
8.
Lu Q, Kishi H, Zhang Y, Morita T, Kobayashi S
J Cardiovasc Pharmacol
. 2022 Jan;
79(4):456-466.
PMID: 34983908
Cardiovascular diseases are the leading cause of mortality and disability worldwide. We have previously found that sphingosylphosphorylcholine (SPC) is the key molecule leading to vasospasm. We have also identified the...
9.
Zhang Y, Kishi H, Morita T, Kobayashi S
FASEB J
. 2021 Nov;
35(12):e22012.
PMID: 34724245
Rho-kinase (ROK)-mediated migration of vascular smooth muscle cells plays a crucial role in cardiovascular diseases. Previously we demonstrated Fyn tyrosine kinase as an upstream molecule of ROK to mediate actin...
10.
Kurahara L, Hiraishi K, Yamamura A, Zhang Y, Abe K, Yahiro E, et al.
J Mol Cell Cardiol
. 2020 Sep;
148:50-62.
PMID: 32889002
Pulmonary arterial hypertension (PAH) is a multifactorial disease characterized by pulmonary arterial vasoconstriction and remodeling. Src family tyrosine kinases, including Fyn, play critical roles in vascular remodeling via the inhibition...