Tofayel Ahmed
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Explore the profile of Tofayel Ahmed including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
204
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Recent Articles
1.
Tyagi A, Ahmed T, Jian S, Bajaj S, Ong S, Goay S, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(5).
PMID: 35091471
We report two structures of the human voltage-gated potassium channel (Kv) Kv1.3 in immune cells alone (apo-Kv1.3) and bound to an immunomodulatory drug called dalazatide (dalazatide-Kv1.3). Both the apo-Kv1.3 and...
2.
Ahmed T, Nisler C, Fluck 3rd E, Walujkar S, Sotomayor M, Moiseenkova-Bell V
Structure
. 2021 Aug;
30(1):139-155.e5.
PMID: 34453887
Transient receptor potential (TRP) channels emerged in fungi as mechanosensitive osmoregulators. The Saccharomyces cerevisiae vacuolar TRP yeast 1 (TRPY1) is the most studied TRP channel from fungi, but the structure...
3.
Tyagi A, Ahmed T, Shi J, Bhushan S
J Struct Biol X
. 2020 Jul;
4:100028.
PMID: 32647830
Zika virus (ZIKV) recently emerged as a major public health concern because it can cause fetal microcephaly and neurological disease such as the Guillain-Barré syndrome. A particularly potent class of...
4.
Pumroy R, Fluck 3rd E, Ahmed T, Moiseenkova-Bell V
Cell Calcium
. 2020 Feb;
87:102168.
PMID: 32004816
Transient Receptor Potential channels from the vanilloid subfamily (TRPV) are a group of cation channels modulated by a variety of endogenous stimuli as well as a range of natural and...
5.
Mishra S, Ahmed T, Tyagi A, Shi J, Bhushan S
Sci Rep
. 2018 Sep;
8(1):13587.
PMID: 30206241
Ribosomes are the dynamic protein synthesis machineries of the cell. They may exist in different functional states in the cell. Therefore, it is essential to have structural information on these...
6.
Ahmed T, Shi J, Bhushan S
Nucleic Acids Res
. 2017 Jun;
45(14):8581-8595.
PMID: 28582576
Chloroplastic translation is mediated by a bacterial-type 70S chloroplast ribosome. During the evolution, chloroplast ribosomes have acquired five plastid-specific ribosomal proteins or PSRPs (cS22, cS23, bTHXc, cL37 and cL38) which...
7.
Belousoff M, Eyal Z, Radjainia M, Ahmed T, Bamert R, Matzov D, et al.
mBio
. 2017 May;
8(3).
PMID: 28487427
An unorthodox, surprising mechanism of resistance to the antibiotic linezolid was revealed by cryo-electron microscopy (cryo-EM) in the 70S ribosomes from a clinical isolate of This high-resolution structural information demonstrated...
8.
Ahmed T, Yin Z, Bhushan S
Sci Rep
. 2016 Oct;
6:35793.
PMID: 27762343
Protein synthesis in the chloroplast is mediated by the chloroplast ribosome (chloro-ribosome). Overall architecture of the chloro-ribosome is considerably similar to the Escherichia coli (E. coli) ribosome but certain differences...
9.
Kumar V, Ero R, Ahmed T, Goh K, Zhan Y, Bhushan S, et al.
J Biol Chem
. 2016 May;
291(25):12943-50.
PMID: 27137929
Elongation factor 4 (EF4) is a member of the family of ribosome-dependent translational GTPase factors, along with elongation factor G and BPI-inducible protein A. Although EF4 is highly conserved in...
10.
Kumar V, Chen Y, Ero R, Ahmed T, Tan J, Li Z, et al.
Proc Natl Acad Sci U S A
. 2015 Aug;
112(35):10944-9.
PMID: 26283392
BPI-inducible protein A (BipA) is a member of the family of ribosome-dependent translational GTPase (trGTPase) factors along with elongation factors G and 4 (EF-G and EF4). Despite being highly conserved...