» Authors » Tobias Sparrman

Tobias Sparrman

Explore the profile of Tobias Sparrman including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 28
Citations 195
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
De Oliveira D, Gowda V, Sparrman T, Gustafsson L, Sanches Pires R, Riekel C, et al.
Nat Commun . 2024 May; 15(1):4670. PMID: 38821983
The major ampullate Spidroin 1 (MaSp1) is the main protein of the dragline spider silk. The C-terminal (CT) domain of MaSp1 is crucial for the self-assembly into fibers but the...
2.
Huynh C, Mavliutova L, Sparrman T, Sellergren B, Irgum K
ACS Omega . 2023 Nov; 8(46):44238-44249. PMID: 38027366
-Acetylneuraminic acid and its α2,3/α2,6-glycosidic linkages with galactose (Neu5Ac-Gal) are major carbohydrate antigen epitopes expressed in various pathological processes, such as cancer, influenza, and SARS-CoV-2. We here report a strategy...
3.
Clifton L, Wacklin-Knecht H, Aden J, Mushtaq A, Sparrman T, Grobner G
Sci Adv . 2023 Jun; 9(22):eadg7940. PMID: 37267355
Apotosis is an essential process tightly regulated by the Bcl-2 protein family where proapoptotic Bax triggers cell death by perforating the mitochondrial outer membrane. Although intensively studied, the molecular mechanism...
4.
Verma A, Aberg-Zingmark E, Sparrman T, Mushtaq A, Rogne P, Grundstrom C, et al.
Sci Adv . 2022 Nov; 8(44):eabm4089. PMID: 36332013
Enzymatic catalysis is critically dependent on selectivity, active site architecture, and dynamics. To contribute insights into the interplay of these properties, we established an approach with NMR, crystallography, and MD...
5.
Mushtaq A, Aden J, Clifton L, Wacklin-Knecht H, Campana M, Dingeldein A, et al.
Commun Biol . 2021 Apr; 4(1):507. PMID: 33907308
B-cell lymphoma 2 (Bcl-2) proteins are the main regulators of mitochondrial apoptosis. Anti-apoptotic Bcl-2 proteins possess a hydrophobic tail-anchor enabling them to translocate to their target membrane and to shift...
6.
Mushtaq A, Aden J, Sparrman T, Hedenstrom M, Grobner G
Molecules . 2021 Apr; 26(5). PMID: 33800399
Evasion from programmed cell death (apoptosis) is the main hallmark of cancer and a major cause of resistance to therapy. Many tumors simply ensure survival by over-expressing the cell-protecting (anti-apoptotic)...
7.
Shamshir A, Dinh N, Jonsson T, Sparrman T, Irgum K
J Chromatogr A . 2020 Jun; 1623:461130. PMID: 32505268
The interactions and dynamic behavior of a select set of polar probe solutes have been investigated on three hydrophilic and polar commercial stationary phases using saturation transfer difference H nuclear...
8.
Liebau J, Tersa M, Trastoy B, Patrick J, Rodrigo-Unzueta A, Corzana F, et al.
J Biol Chem . 2020 May; 295(29):9868-9878. PMID: 32434931
Fold-switch pathways remodel the secondary structure topology of proteins in response to the cellular environment. It is a major challenge to understand the dynamics of these folding processes. Here, we...
9.
Shamshir A, Dinh N, Jonsson T, Sparrman T, Ashiq M, Irgum K
J Chromatogr A . 2019 Feb; 1588:58-67. PMID: 30704776
Toluene has been used as void volume (zero retention) marker since the inception of hydrophilic interaction chromatography (HILIC), based on the assumption that its hydrophobicity should prevent it from interacting...
10.
Song Y, Jiang T, Liem-Nguyen V, Sparrman T, Bjorn E, Skyllberg U
Environ Sci Technol . 2018 Jul; 52(15):8292-8301. PMID: 29983050
A molecular level understanding of the thermodynamics and kinetics of the chemical bonding between mercury, Hg(II), and natural organic matter (NOM) associated thiol functional groups (NOM-RSH) is required if bioavailability...