Tobias Kessler
Overview
Explore the profile of Tobias Kessler including associated specialties, affiliations and a list of published articles.
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Articles
70
Citations
2060
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Recent Articles
1.
Cebulla G, Hai L, Warnken U, Gungor C, Hoffmann D, Korporal-Kuhnke M, et al.
J Neurol
. 2025 Mar;
272(4):270.
PMID: 40085221
Background: 5q-associated spinal muscular atrophy (SMA) is a monogenic disease causing progressive alpha motor neuron degeneration, muscle atrophy, and weakness. Intrathecal therapy with the antisense oligonucleotide nusinersen modifies the disease...
2.
Cordts I, Fuetterer C, Wachinger A, von Heynitz R, Kessler T, Freigang M, et al.
Neurology
. 2025 Feb;
104(5):e213371.
PMID: 39946662
Background And Objectives: The availability of disease-modifying therapies for 5q-associated spinal muscular atrophy (SMA) has heightened the need to identify suitable biomarkers. This study investigates neurofilament light chain (NfL) concentrations...
3.
Riviere-Cazaux C, Keough M, Zuccato J, Kumar R, Schulz S, Warrington A, et al.
Neuro Oncol
. 2025 Jan;
PMID: 39786477
Cerebrospinal fluid (CSF) has emerged as a valuable liquid biopsy source for glioma biomarker discovery and validation. CSF produced within the ventricles circulates through the subarachnoid space, where the composition...
4.
Foltyn-Dumitru M, Rastogi A, Cho J, Schell M, Mahmutoglu M, Kessler T, et al.
Neurooncol Adv
. 2025 Jan;
7(1):vdae230.
PMID: 39780768
Background: This study aimed to explore the potential of the Advanced Data Analytics (ADA) package of GPT-4 to autonomously develop machine learning models (MLMs) for predicting glioma molecular types using...
5.
Ippen F, Scherm A, Kessler T, Hau P, Agkatsev S, Baurecht H, et al.
Cancer Med
. 2024 Dec;
13(12):e7362.
PMID: 39618405
Background: Glioblastoma (GB) is the most common malignant primary brain tumor in adults and is associated with a poor prognosis. Current treatment guidelines outline the standard of care for patients...
6.
Hai L, Friedel D, Hinz F, Hoffmann D, Doubrovinskaia S, Rohdjess H, et al.
Neuro Oncol
. 2024 Nov;
PMID: 39575767
Background: Epstein-Barr virus (EBV)+ and EBV- primary CNS lymphomas (PCNSL) carry distinct mutational landscapes, but their transcriptional and epigenetic profiles have not been integrated and compared. This precludes further insights...
7.
Alhalabi O, Gottmann M, Gold M, Schlue S, Hielscher T, Iskar M, et al.
Cancer Lett
. 2024 Sep;
605:217265.
PMID: 39332586
Glioblastoma is characterized by a pronounced resistance to therapy with dismal prognosis. Transcriptomics classify glioblastoma into proneural (PN), mesenchymal (MES) and classical (CL) subtypes that show differential resistance to targeted...
8.
Foltyn-Dumitru M, Mahmutoglu M, Brugnara G, Kessler T, Sahm F, Wick W, et al.
Eur Radiol
. 2024 Sep;
35(3):1351-1360.
PMID: 39251442
Objectives: This study examines clustering based on shape radiomic features and tumor volume to identify IDH-wildtype glioma phenotypes and assess their impact on overall survival (OS). Materials And Methods: This...
9.
Kaulen L, Hielscher T, Doubrovinskaia S, Hoffmann D, Kessler T, Traub B, et al.
Neurology
. 2024 Aug;
103(4):e209698.
PMID: 39102613
Background And Objectives: Neurolymphomatosis (NL) refers to lymphomatous infiltration of the peripheral nervous system (PNS). NL diagnosis and treatment are challenging given the broad differential diagnosis of peripheral neuropathy, the...
10.
Foltyn-Dumitru M, Alzaid H, Rastogi A, Neuberger U, Sahm F, Kessler T, et al.
Neurooncol Adv
. 2024 Jul;
6(1):vdae112.
PMID: 39022646
Background: The purpose of this study was to elucidate the relationship between distinct brain regions and molecular subtypes in glioblastoma (GB), focusing on integrating modern statistical tools and molecular profiling...