Frank Winkler
Overview
Explore the profile of Frank Winkler including associated specialties, affiliations and a list of published articles.
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144
Citations
7098
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Recent Articles
1.
Thiel V, Renders S, Panten J, Dross N, Bauer K, Azorin D, et al.
Nature
. 2025 Feb;
PMID: 39961335
The peripheral nervous system (PNS) orchestrates organ function in health and disease. Most cancers including pancreatic ductal adenocarcinoma (PDAC) are infiltrated by PNS neurons, contributing to the complex tumor microenvironment...
2.
Venkataramani V, Yang Y, Ille S, Suchorska B, Loges S, Tost H, et al.
Cancer Discov
. 2025 Jan;
15(1):39-51.
PMID: 39801234
Deepening our understanding of neuro-cancer interactions can innovate brain tumor treatment. This mini review unfolds the most relevant and recent insights into the neural mechanisms contributing to brain tumor initiation,...
3.
Karimian-Jazi K, Enbergs N, Golubtsov E, Schregel K, Ungermann J, Fels-Palesandro H, et al.
Invest Radiol
. 2024 Dec;
PMID: 39644107
Objectives: Recurrent glioma is highly treatment resistant due to its metabolic, cellular, and molecular heterogeneity and invasiveness. Tumor monitoring by conventional MRI has shortcomings to assess these key glioma characteristics....
4.
Kats I, Simovic-Lorenz M, Schreiber H, Sant P, Mallm J, Korber V, et al.
Nat Commun
. 2024 Nov;
15(1):10370.
PMID: 39609432
Paediatric medulloblastomas with chromothripsis are characterised by high genomic instability and are among the tumours with the worst prognosis. However, the molecular makeup and the determinants of the aggressiveness of...
5.
Messmer J, Thommek C, Piechutta M, Venkataramani V, Wehner R, Westphal D, et al.
Immunity
. 2024 Oct;
57(11):2688-2703.e11.
PMID: 39368486
To improve immunotherapy for brain tumors, it is important to determine the principal intracranial site of T cell recruitment from the bloodstream and their intracranial route to brain tumors. Using...
6.
Schubert M, Soyka S, Tamimi A, Maus E, Schroers J, Wissmann N, et al.
Nat Commun
. 2024 Sep;
15(1):7383.
PMID: 39256378
Intravital 2P-microscopy enables the longitudinal study of brain tumor biology in superficial mouse cortex layers. Intravital microscopy of the white matter, an important route of glioblastoma invasion and recurrence, has...
7.
Fels-Palesandro H, Heuer S, Boztepe B, Streibel Y, Ungermann J, Pan C, et al.
J Magn Reson Imaging
. 2024 Aug;
61(3):1203-1218.
PMID: 39177509
Background: Gliomas are highly invasive brain neoplasms. MRI is the most important tool to diagnose and monitor glioma but has shortcomings. In particular, the assessment of tumor cell invasion is...
8.
Streibel Y, Breckwoldt M, Hunger J, Pan C, Fischer M, Turco V, et al.
Sci Rep
. 2024 Jul;
14(1):15613.
PMID: 38971907
Glioblastoma is the most common and aggressive primary malignant brain tumor with poor prognosis. Novel immunotherapeutic approaches are currently under investigation. Even though magnetic resonance imaging (MRI) is the most...
9.
Amit M, Anastasaki C, Dantzer R, Demir I, Deneen B, Dixon K, et al.
Cancer Discov
. 2024 Apr;
14(4):669-673.
PMID: 38571430
The field of cancer neuroscience has begun to define the contributions of nerves to cancer initiation and progression; here, we highlight the future directions of basic and translational cancer neuroscience...
10.
Swanton C, Bernard E, Abbosh C, Andre F, Auwerx J, Balmain A, et al.
Cell
. 2024 Mar;
187(7):1589-1616.
PMID: 38552609
The last 50 years have witnessed extraordinary developments in understanding mechanisms of carcinogenesis, synthesized as the hallmarks of cancer. Despite this logical framework, our understanding of the molecular basis of...