Timmy Le
Overview
Explore the profile of Timmy Le including associated specialties, affiliations and a list of published articles.
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9
Citations
82
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Recent Articles
1.
Andromidas F, Mackinnon B, Myers A, Shaffer M, Brahimi A, Atashpanjeh S, et al.
Mol Cell Neurosci
. 2024 Oct;
131:103975.
PMID: 39368763
Astrocytes are tasked with regulating the synaptic environment. Early stages of various neurodegenerative diseases are characterized by synapse loss, and astrocytic atrophy and dysfunction has been proposed as a possible...
2.
Gimenez-Gomez P, Le T, Martin G
Front Mol Neurosci
. 2023 Mar;
16:1098211.
PMID: 36866357
Drug use poses a serious threat to health systems throughout the world. The number of consumers rises every year being alcohol the drug of abuse most consumed causing 3 million...
3.
Kolpakova J, van der Vinne V, Gimenez-Gomez P, Le T, Martin G
Front Cell Neurosci
. 2023 Jan;
16:1010121.
PMID: 36589290
Animals studies support the notion that striatal cholinergic interneurons (ChIs) play a central role in basal ganglia function by regulating associative learning, reward processing, and motor control. In the nucleus...
4.
Kolpakova J, van der Vinne V, Gimenez-Gomez P, Le T, You I, Zhao-Shea R, et al.
Front Cell Neurosci
. 2021 Dec;
15:742207.
PMID: 34867199
The nucleus accumbens (NAc) is a forebrain region mediating the positive-reinforcing properties of drugs of abuse, including alcohol. It receives glutamatergic projections from multiple forebrain and limbic regions such as...
5.
Huang L, Le T, Huang K, Han G
Nat Commun
. 2021 Mar;
12(1):1898.
PMID: 33772017
Triplet-triplet annihilation upconversion nanoparticles have attracted considerable interest due to their promises in organic chemistry, solar energy harvesting and several biological applications. However, triplet-triplet annihilation upconversion in aqueous solutions is...
6.
Specific Neuroligin3-αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus
Uchigashima M, Konno K, Demchak E, Cheung A, Watanabe T, Keener D, et al.
Elife
. 2020 Dec;
9.
PMID: 33355091
Synapse formation and regulation require signaling interactions between pre- and postsynaptic proteins, notably cell adhesion molecules (CAMs). It has been proposed that the functions of neuroligins (Nlgns), postsynaptic CAMs, rely...
7.
Uchigashima M, Leung M, Watanabe T, Cheung A, Le T, Pallat S, et al.
J Biol Chem
. 2020 May;
295(25):8589-8595.
PMID: 32381505
Synapse formation is a dynamic process essential for the development and maturation of the neuronal circuitry in the brain. At the synaptic cleft, trans-synaptic protein-protein interactions are major biological determinants...
8.
Le T, Winham C, Andromidas F, Silver A, Jellison E, Levesque A, et al.
Neural Regen Res
. 2020 Apr;
15(10):1894-1902.
PMID: 32246638
Elevated levels of γ-synuclein (γ-syn) expression have been noted in the progression of glioblastomas, and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases. γ-Syn can be either...
9.
Winham C, Le T, Jellison E, Silver A, Levesque A, Koob A
Neuroscience
. 2019 May;
410:41-54.
PMID: 31078687
γ-Synuclein (γ-syn) is expressed by astrocytes in the human nervous system, and increased extracellularly in the brain and cerebrospinal fluid of individuals diagnosed with Alzheimer's disease. Upregulation of γ-syn also...