Andrew O Koob
Overview
Explore the profile of Andrew O Koob including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
350
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0
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Recent Articles
1.
Koob A, Shaked G, Bender A, Bisquertt A, Rockenstein E, Masliah E
Brain Res
. 2025 Feb;
1851:149504.
PMID: 39947974
No abstract available.
2.
Andromidas F, Mackinnon B, Myers A, Shaffer M, Brahimi A, Atashpanjeh S, et al.
Mol Cell Neurosci
. 2024 Oct;
131:103975.
PMID: 39368763
Astrocytes are tasked with regulating the synaptic environment. Early stages of various neurodegenerative diseases are characterized by synapse loss, and astrocytic atrophy and dysfunction has been proposed as a possible...
3.
Myers A, Brahimi A, Jenkins I, Koob A
Biology (Basel)
. 2023 Feb;
12(2).
PMID: 36829434
Synucleins consist of three proteins exclusively expressed in vertebrates. α-Synuclein (αS) has been identified as the main proteinaceous aggregate in Lewy bodies, a pathological hallmark of many neurodegenerative diseases. Less...
4.
Koob A
J Integr Neurosci
. 2022 Jul;
21(4):112.
PMID: 35864764
The cellular, molecular and physiological basis of cognition has proved elusive until emerging studies on astrocytes. The appearance of a deliberate aggregating element in cellular neurophysiology was difficult to satisfy...
5.
Koob A, Ballantyne S, Levesque A, Qureshi A, Congdon S
J Undergrad Neurosci Educ
. 2022 May;
20(1):A1-A10.
PMID: 35540948
DNA segments with variable number tandem repeats (VNTR) serve as a model for students to learn DNA extraction and polymerase chain reaction (PCR) techniques in biology laboratory courses from the...
6.
Andromidas F, Atashpanjeh S, Myers A, Mackinnon B, Shaffer M, Koob A
Curr Neuropharmacol
. 2021 Apr;
19(11):1952-1965.
PMID: 33881971
An inverse correlation between the incidence of cancer and neurodegenerative disease has been observed, with the prevalence of cancer peaking around 60 years of age, then slowly tapering off as...
7.
Le T, Winham C, Andromidas F, Silver A, Jellison E, Levesque A, et al.
Neural Regen Res
. 2020 Apr;
15(10):1894-1902.
PMID: 32246638
Elevated levels of γ-synuclein (γ-syn) expression have been noted in the progression of glioblastomas, and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases. γ-Syn can be either...
8.
Winham C, Le T, Jellison E, Silver A, Levesque A, Koob A
Neuroscience
. 2019 May;
410:41-54.
PMID: 31078687
γ-Synuclein (γ-syn) is expressed by astrocytes in the human nervous system, and increased extracellularly in the brain and cerebrospinal fluid of individuals diagnosed with Alzheimer's disease. Upregulation of γ-syn also...
9.
10.
Mohn T, Koob A
J Exp Neurosci
. 2015 Nov;
9(Suppl 2):25-34.
PMID: 26568684
As more evidence points to a clear role for astrocytes in synaptic processing, synaptogenesis and cognition, continuing research on astrocytic function could lead to strategies for neurodegenerative disease prevention. Reactive...