Tim Guo
Overview
Explore the profile of Tim Guo including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
48
Followers
0
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Recent Articles
1.
Lehman S, Vreeland W, Blaszczyk A, Adams-Hall S, Ahuja S, Arnaout A, et al.
Hum Gene Ther
. 2024 Dec;
36(1-2):36-44.
PMID: 39723438
Recombinant adeno-associated virus (AAV) is one of the main viral vector-based gene therapy platforms. AAV is a virus consisting of a ≈25 nm diameter capsid with a ≈4.7 kb cargo...
2.
Decor A, Grand-Maitre C, Hucke O, OMeara J, Kuhn C, Constantineau-Forget L, et al.
Bioorg Med Chem Lett
. 2013 Jun;
23(13):3841-7.
PMID: 23726345
We describe here the design, synthesis and biological evaluation of antiviral compounds acting against human rhinovirus (HRV). A series of aminothiazoles demonstrated pan-activity against the HRV genotypes screened and productive...
3.
Spickler C, Lippens J, Laberge M, Desmeules S, Bellavance E, Garneau M, et al.
Antimicrob Agents Chemother
. 2013 May;
57(7):3358-68.
PMID: 23650168
Human rhinovirus (HRV) is the predominant cause of the common cold, but more importantly, infection may have serious repercussions in asthmatics and chronic obstructive pulmonary disorder (COPD) patients. A cell-based...
4.
Manku S, Allan M, Nguyen N, Ajamian A, Rodrigue J, Therrien E, et al.
Bioorg Med Chem Lett
. 2009 Mar;
19(7):1866-70.
PMID: 19272776
We have recently reported on a novel class of histone deacetylase (HDAC) inhibitors bearing a sulfamide group as the zinc-binding unit. Herein, we report on the synthesis of sulfamide based...