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Annick Gauthier

Explore the profile of Annick Gauthier including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 373
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Recent Articles
1.
Auger N, Luu T, Healy-Profitos J, Gauthier A, Lo E, Fraser W
J Stud Alcohol Drugs . 2018 Aug; 79(4):553-560. PMID: 30079870
Objective: Infants with neonatal abstinence syndrome have significant morbidity, but the association with birth defects is poorly understood. This study aimed to determine how neonatal abstinence syndrome is related to...
2.
Perreira J, Aker A, Savidis G, Chin C, McDougall W, Portmann J, et al.
Cell Rep . 2015 Jul; 12(5):850-63. PMID: 26212330
Human rhinovirus (HRV) causes upper respiratory infections and asthma exacerbations. We screened multiple orthologous RNAi reagents and identified host proteins that modulate HRV replication. Here, we show that RNASEK, a...
3.
Jacob C, Lamorte L, Sepulveda E, Lorenz I, Gauthier A, Franti M
Virology . 2013 Jul; 444(1-2):140-7. PMID: 23849792
Infection with human cytomegalovirus (CMV) during pregnancy is the most common cause of congenital disorders, and can lead to severe life-long disabilities with associated high cost of care. Since there...
4.
Decor A, Grand-Maitre C, Hucke O, OMeara J, Kuhn C, Constantineau-Forget L, et al.
Bioorg Med Chem Lett . 2013 Jun; 23(13):3841-7. PMID: 23726345
We describe here the design, synthesis and biological evaluation of antiviral compounds acting against human rhinovirus (HRV). A series of aminothiazoles demonstrated pan-activity against the HRV genotypes screened and productive...
5.
Spickler C, Lippens J, Laberge M, Desmeules S, Bellavance E, Garneau M, et al.
Antimicrob Agents Chemother . 2013 May; 57(7):3358-68. PMID: 23650168
Human rhinovirus (HRV) is the predominant cause of the common cold, but more importantly, infection may have serious repercussions in asthmatics and chronic obstructive pulmonary disorder (COPD) patients. A cell-based...
6.
Gervais C, Do F, Cantin A, Kukolj G, White P, Gauthier A, et al.
J Biomol Screen . 2011 Feb; 16(3):363-9. PMID: 21343600
The HCV p7 protein is not involved in viral RNA replication but is essential for production of infectious virus. Based on its putative ion channel activity, p7 belongs to a...
7.
Gutierrez J, Klepper A, Garber J, Walewski J, Bateman K, Khaitova V, et al.
J Virol Methods . 2010 Nov; 171(1):169-75. PMID: 21034775
Many anti-HCV antibodies are available, but more are needed for research and clinical applications. This study examines whether ascitic fluid from cirrhotic patients could be a source of reagent-grade antibodies....
8.
Linington R, Robertson M, Gauthier A, Finlay B, MacMillan J, Molinski T, et al.
J Nat Prod . 2006 Feb; 69(2):173-7. PMID: 16499312
A screening program aimed at discovering inhibitors of the bacterial type III secretion system identified the MeOH extract of the Caribbean sponge Caminus sphaeroconia as an active hit in the...
9.
Gauthier A, Robertson M, Lowden M, Ibarra J, Puente J, Finlay B
Antimicrob Agents Chemother . 2005 Sep; 49(10):4101-9. PMID: 16189086
The type III secretion system (TTSS) is a key virulence mechanism of many important gram-negative bacterial pathogens. The TTSS is conserved among different bacterial pathogens, and mutations and deletions to...
10.
Gauthier A, Finlay B
J Bacteriol . 2003 Nov; 185(23):6747-55. PMID: 14617638
Few interactions have been reported between effectors and components of the type III secretion apparatus, although many interactions have been demonstrated between type III effectors and their cognate chaperones. It...