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Till Bartke

Explore the profile of Till Bartke including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1727
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Recent Articles
1.
Tvardovskiy A, Lukauskas S, Bartke T
Epigenomics . 2024 Sep; 16(15-16):1061-1065. PMID: 39229639
No abstract available.
2.
Stadler M, Lukauskas S, Bartke T, Muller C
Nucleic Acids Res . 2024 May; 52(11):6129-6144. PMID: 38752495
Chromatin, the nucleoprotein complex consisting of DNA and histone proteins, plays a crucial role in regulating gene expression by controlling access to DNA. Chromatin modifications are key players in this...
3.
Lukauskas S, Tvardovskiy A, Nguyen N, Stadler M, Faull P, Ravnsborg T, et al.
Nature . 2024 Apr; 628(8009):E6. PMID: 38594341
No abstract available.
4.
Yamaguchi K, Chen X, Rodgers B, Miura F, Bashtrykov P, Bonhomme F, et al.
Nat Commun . 2024 Apr; 15(1):2960. PMID: 38580649
DNA methylation is an essential epigenetic chromatin modification, and its maintenance in mammals requires the protein UHRF1. It is yet unclear if UHRF1 functions solely by stimulating DNA methylation maintenance...
5.
Lukauskas S, Tvardovskiy A, Nguyen N, Stadler M, Faull P, Ravnsborg T, et al.
Nature . 2024 Mar; 627(8004):671-679. PMID: 38448585
DNA and histone modifications combine into characteristic patterns that demarcate functional regions of the genome. While many 'readers' of individual modifications have been described, how chromatin states comprising composite modification...
6.
Karl L, Galanti L, Bantele S, Metzner F, Safaric B, Rajappa L, et al.
Life Sci Alliance . 2023 Jul; 6(9). PMID: 37468166
Fun30 is the prototype of the Fun30-SMARCAD1-ETL subfamily of nucleosome remodelers involved in DNA repair and gene silencing. These proteins appear to act as single-subunit nucleosome remodelers, but their molecular...
7.
Stolz P, Salazar Mantero A, Tvardovskiy A, Ugur E, Wange L, Mulholland C, et al.
Nucleic Acids Res . 2022 Jul; 50(15):8491-8511. PMID: 35904814
DNA methylation (5-methylcytosine (5mC)) is critical for genome stability and transcriptional regulation in mammals. The discovery that ten-eleven translocation (TET) proteins catalyze the oxidation of 5mC to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine...
8.
Tvardovskiy A, Nguyen N, Bartke T
Methods Mol Biol . 2022 Jun; 2529:327-403. PMID: 35733023
Chemical modification of histone proteins by methylation plays a central role in chromatin regulation by recruiting epigenetic "readers" via specialized binding domains. Depending on the degree of methylation, the exact...
9.
Skalska L, Begley V, Beltran M, Lukauskas S, Khandelwal G, Faull P, et al.
Mol Cell . 2021 Jun; 81(14):2944-2959.e10. PMID: 34166609
A number of regulatory factors are recruited to chromatin by specialized RNAs. Whether RNA has a more general role in regulating the interaction of proteins with chromatin has not been...
10.
Santos-Rosa H, Millan-Zambrano G, Han N, Leonardi T, Klimontova M, Nasiscionyte S, et al.
Mol Cell . 2021 May; 81(13):2793-2807.e8. PMID: 33979575
DNA replication initiates at genomic locations known as origins of replication, which, in S. cerevisiae, share a common DNA consensus motif. Despite being virtually nucleosome-free, origins of replication are greatly...