Tibor Pakozdi
Overview
Explore the profile of Tibor Pakozdi including associated specialties, affiliations and a list of published articles.
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7
Citations
468
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Recent Articles
1.
Stolzenburg L, Ainsworth B, Riley-Gillis B, Pakozdi T, Ammar A, Ellis P, et al.
Oncotarget
. 2022 Jan;
13:1-12.
PMID: 35018214
Inhibitors of poly(ADP)-ribose polymerase (PARP) exploit defective DNA repair pathways existing in several forms of cancer, such as those with BRCA mutations, and have proven clinical efficacy as chemosensitizers. However,...
2.
Alekseyenko A, Walsh E, Zee B, Pakozdi T, Hsi P, Lemieux M, et al.
Proc Natl Acad Sci U S A
. 2017 May;
114(21):E4184-E4192.
PMID: 28484033
To investigate the mechanism that drives dramatic mistargeting of active chromatin in NUT midline carcinoma (NMC), we have identified protein interactions unique to the BRD4-NUT fusion oncoprotein compared with wild-type...
3.
Dual functionality of -regulatory elements as developmental enhancers and Polycomb response elements
Erceg J, Pakozdi T, Marco-Ferreres R, Ghavi-Helm Y, Girardot C, Bracken A, et al.
Genes Dev
. 2017 Apr;
31(6):590-602.
PMID: 28381411
Developmental gene expression is tightly regulated through enhancer elements, which initiate dynamic spatio-temporal expression, and Polycomb response elements (PREs), which maintain stable gene silencing. These two -regulatory functions are thought...
4.
Ghavi-Helm Y, Klein F, Pakozdi T, Ciglar L, Noordermeer D, Huber W, et al.
Nature
. 2016 Jul;
537(7619):254.
PMID: 27409805
No abstract available.
5.
Klein F, Pakozdi T, Anders S, Ghavi-Helm Y, Furlong E, Huber W
Bioinformatics
. 2015 Jun;
31(19):3085-91.
PMID: 26034064
Motivation: Circularized Chromosome Conformation Capture (4C) is a powerful technique for studying the spatial interactions of a specific genomic region called the 'viewpoint' with the rest of the genome, both...
6.
Ghavi-Helm Y, Klein F, Pakozdi T, Ciglar L, Noordermeer D, Huber W, et al.
Nature
. 2014 Jul;
512(7512):96-100.
PMID: 25043061
Developmental enhancers initiate transcription and are fundamental to our understanding of developmental networks, evolution and disease. Despite their importance, the properties governing enhancer-promoter interactions and their dynamics during embryogenesis remain...
7.
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, et al.
Mol Cell Biol
. 2012 Jul;
32(19):3814-22.
PMID: 22801375
RUNX1 is known to be an essential transcription factor for generating hematopoietic stem cells (HSC), but much less is known about its role in the downstream process of hematopoietic differentiation....