Thomas Weidemann
Overview
Explore the profile of Thomas Weidemann including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
566
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Recent Articles
1.
Steiert F, Schultz P, Hofinger S, Muller T, Schwille P, Weidemann T
Nat Commun
. 2023 Mar;
14(1):1596.
PMID: 36949079
Evaluating protein structures in living cells remains a challenge. Here, we investigate Interleukin-4 receptor alpha (IL-4Rα) into which the non-canonical amino acid bicyclo[6.1.0]nonyne-lysine (BCNK) is incorporated by genetic code expansion....
2.
Lemke S, Weidemann T, Cost A, Grashoff C, Schnorrer F
PLoS Biol
. 2019 Mar;
17(3):e3000057.
PMID: 30917109
Cells in developing organisms are subjected to particular mechanical forces that shape tissues and instruct cell fate decisions. How these forces are sensed and transmitted at the molecular level is...
3.
Steiert F, Petrov E, Schultz P, Schwille P, Weidemann T
Biophys J
. 2018 May;
114(10):2419-2431.
PMID: 29706225
Fluorescent proteins (FPs) feature complex photophysical behavior that must be considered when studying the dynamics of fusion proteins in model systems and live cells. In this work, we characterize mNeonGreen...
4.
Worch R, Petrasek Z, Schwille P, Weidemann T
J Membr Biol
. 2016 Nov;
250(4):393-406.
PMID: 27826635
To quantitatively examine the effect of membrane organization on lateral diffusion, we studied fluorescent carbocyanine lipid analogues and EGFP-tagged, single-pass transmembrane proteins in systems of decreasing complexity: (i) the plasma...
5.
Pylypenko O, Welz T, Tittel J, Kollmar M, Chardon F, Malherbe G, et al.
Elife
. 2016 Sep;
5.
PMID: 27623148
There is growing evidence for a coupling of actin assembly and myosin motor activity in cells. However, mechanisms for recruitment of actin nucleators and motors on specific membrane compartments remain...
6.
Heusermann W, Ludin B, Pham N, Auer M, Weidemann T, Hintersteiner M
ACS Comb Sci
. 2016 Apr;
18(5):209-19.
PMID: 27057765
The increasing involvement of academic institutions and biotech companies in drug discovery calls for cost-effective methods to identify new bioactive molecules. Affinity-based on-bead screening of combinatorial one-bead one-compound libraries combines...
7.
Sanchez M, Levi V, Weidemann T, Carrer D
FEBS Lett
. 2015 Oct;
589(23):3527-33.
PMID: 26484594
Extrinsic apoptosis is initiated by recognition and clustering of the single-pass transmembrane proteins Fas ligand and Fas expressed at the surface of closely apposed lymphocytes and target cells, respectively. Since...
8.
Kurgonaite K, Gandhi H, Kurth T, Pautot S, Schwille P, Weidemann T, et al.
J Cell Sci
. 2015 Aug;
128(20):3781-95.
PMID: 26306492
Many important signalling cascades operate through specialized signalling endosomes, but a corresponding mechanism has as yet not been described for hematopoietic cytokine receptors. Based on live-cell affinity measurements, we recently...
9.
Tittel J, Welz T, Czogalla A, Dietrich S, Samol-Wolf A, Schulte M, et al.
J Biol Chem
. 2015 Jan;
290(10):6428-44.
PMID: 25564607
Spir and formin (FMN)-type actin nucleators initiate actin polymerization at vesicular membranes necessary for long range vesicular transport processes. Here we studied in detail the membrane binding properties and protein/protein...
10.
Gandhi H, Worch R, Kurgonaite K, Hintersteiner M, Schwille P, Bokel C, et al.
Biophys J
. 2014 Dec;
107(11):2515-27.
PMID: 25468331
It has long been established that dimerization of Interleukin-4 receptor (IL-4R) subunits is a pivotal step for JAK/STAT signal transduction. However, ligand-induced complex formation at the surface of living cells...