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Thomas W Scully

Explore the profile of Thomas W Scully including associated specialties, affiliations and a list of published articles. Areas
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Citations 17
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Recent Articles
1.
Scully T, Jiao W, Mittelstadt G, Parker E
Philos Trans R Soc Lond B Biol Sci . 2023 Jan; 378(1871):20220039. PMID: 36633281
Anthranilate phosphoribosyltransferase catalyses the second reaction in the biosynthesis of tryptophan from chorismate in microorganisms and plants. The enzyme is homodimeric with the active site located in the hinge region...
2.
Stanton J, OBrien R, Hall R, Chernyavtseva A, Ha H, Jelley L, et al.
Front Public Health . 2022 Feb; 9:808751. PMID: 35141190
The rapid global rise of COVID-19 from late 2019 caught major manufacturers of RT-qPCR reagents by surprise and threw into sharp focus the heavy reliance of molecular diagnostic providers on...
3.
Soueidan O, Scully T, Kaur J, Panigrahi R, Belovodskiy A, Do V, et al.
ACS Chem Biol . 2017 Feb; 12(4):1087-1094. PMID: 28205432
The specificity characteristics of transporters can be exploited for the development of novel diagnostic therapeutic probes. The facilitated hexose transporter family (GLUTs) has a distinct set of preferences for monosaccharide...
4.
Schatz D, Kwon Y, Scully T, West F
J Org Chem . 2016 Dec; 81(24):12494-12498. PMID: 27978732
The generation of dibrominated cyclopentenones via an interrupted Nazarov cyclization is reported. The installation of two bromine atoms occurs at the α and α' positions of the cyclopentenyl scaffold via...
5.
Plourde G, Scully T
Molecules . 2013 Jan; 18(1):1174-80. PMID: 23344206
A short five steps synthesis of the title compound from vanillin is described. The racemic spiroether 7 was obtained in 61% yield and in >99% diastereomeric excess (by 1H-NMR) from...
6.
Plourde G, Spaetzel R, Kwasnitza J, Scully T
Molecules . 2007 Oct; 12(9):2215-22. PMID: 17962738
The asymmetric syntheses of two new spirolactones prepared in optically pure form from L-3-nitrotyrosine are described. The key step, an oxidative spiroannulation, was carried out on the optically active phenols...