Thomas S Kilduff
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Explore the profile of Thomas S Kilduff including associated specialties, affiliations and a list of published articles.
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83
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2386
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Recent Articles
31.
Cortical nNOS/NK1 Receptor Neurons are Regulated by Cholinergic Projections From the Basal Forebrain
Williams R, Vazquez-DeRose J, Thomas A, Piquet J, Cauli B, Kilduff T
Cereb Cortex
. 2017 May;
28(6):1959-1979.
PMID: 28472227
Cholinergic (ACh) basal forebrain (BF) neurons are active during wakefulness and rapid eye movement (REM) sleep and are involved in sleep homeostasis. We have previously shown in adult animals that...
32.
Thomas A, Schwartz M, Saxe M, Kilduff T
Sleep
. 2017 Apr;
40(1).
PMID: 28364455
Study Objectives: Although recent innovations have enabled modification of the rat genome, it is unclear whether enhanced utility of rodents as human disease models will result. We compared electroencephalogram (EEG)...
33.
Peyron C, Kilduff T
J Neurosci
. 2017 Mar;
37(9):2268-2272.
PMID: 28250055
Early in 1998, we (de Lecea et al., 1998) and others (Sakurai et al., 1998) described the same hypothalamic neuropeptides, respectively called the hypocretins or orexins, which were discovered using...
34.
Black S, Schwartz M, Chen T, Hoener M, Kilduff T
Biol Psychiatry
. 2016 Dec;
82(9):623-633.
PMID: 27919403
Background: Narcolepsy, a disorder of rapid eye movement (REM) sleep, is characterized by excessive daytime sleepiness and cataplexy, a loss of muscle tone triggered by emotional stimulation. Current narcolepsy pharmacotherapeutics...
35.
Schwartz M, Black S, Fisher S, Palmerston J, Morairty S, Hoener M, et al.
Neuropsychopharmacology
. 2016 Sep;
42(6):1305-1314.
PMID: 27658486
Trace amine-associated receptor 1 (TAAR1) agonists have been shown to have procognitive, antipsychotic-like, anxiolytic, weight-reducing, glucose-lowering, and wake-promoting activities. We used Taar1 knockout (KO) and overexpressing (OE) mice and TAAR1...
36.
Schwartz M, Nguyen A, Warrier D, Palmerston J, Thomas A, Morairty S, et al.
eNeuro
. 2016 Mar;
3(2).
PMID: 27022631
Hypocretin 1 and 2 (Hcrts; also known as orexin A and B), excitatory neuropeptides synthesized in cells located in the tuberal hypothalamus, play a central role in the control of...
37.
Black S, Kilduff T
Proc Natl Acad Sci U S A
. 2016 Jan;
113(3):476-7.
PMID: 26747601
No abstract available.
38.
Black S, Yamanaka A, Kilduff T
Prog Neurobiol
. 2016 Jan;
152:89-113.
PMID: 26721620
Narcolepsy is a neurological disorder that afflicts 1 in 2000 individuals and is characterized by excessive daytime sleepiness and cataplexy-a sudden loss of muscle tone triggered by positive emotions. Features...
39.
Schwartz M, Kilduff T
Psychiatr Clin North Am
. 2015 Nov;
38(4):615-44.
PMID: 26600100
Cortical electroencephalographic activity arises from corticothalamocortical interactions, modulated by wake-promoting monoaminergic and cholinergic input. These wake-promoting systems are regulated by hypothalamic hypocretin/orexins, while GABAergic sleep-promoting nuclei are found in the...
40.
Fisher S, Schwartz M, Wurts-Black S, Thomas A, Chen T, Miller M, et al.
Sleep
. 2015 Oct;
39(2):379-91.
PMID: 26446107
Study Objectives: Patients with Huntington's disease (HD) show a high prevalence of sleep disorders that typically occur prior to the onset of motoric symptoms and neurodegeneration. Our understanding of the...