Thomas J Upton
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Explore the profile of Thomas J Upton including associated specialties, affiliations and a list of published articles.
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Articles
2
Citations
16
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Recent Articles
1.
Klaas S, Upton T, Zavala E, Lawton M, Bensing S, Berinder K, et al.
Proc Biol Sci
. 2025 Jan;
292(2038):20241844.
PMID: 39809311
Cortisol is released upon activation of the hypothalamic-pituitary-adrenal axis, varies across the day, possesses an underlying diurnal rhythm and is responsive to stressors. The endogenous circadian peak of cortisol occurs...
2.
Upton T, Zavala E, Methlie P, Kampe O, Tsagarakis S, Oksnes M, et al.
Sci Transl Med
. 2023 Jun;
15(701):eadg8464.
PMID: 37343084
Rhythms are intrinsic to endocrine systems, and disruption of these hormone oscillations occurs at very early stages of the disease. Because adrenal hormones are secreted with both circadian and ultradian...
3.
Grant A, Upton T, Terry J, Smarr B, Zavala E
Curr Opin Endocr Metab Res
. 2023 Jan;
25:100380.
PMID: 36632470
Many hormones in the body oscillate with different frequencies and amplitudes, creating a dynamic environment that is essential to maintain health. In humans, disruptions to these rhythms are strongly associated...